小切口白内障囊外摘除术治疗硬核白内障患者的有效性与安全性  

Efficacy and safety of small-incision extracapsular cataract extraction in the treatment of patients with hard nuclear cataract

作　　者：蒲艳妮 黄蓓 PU Yanni;HUANG Bei(Shaanxi Kangfu Hospital,Xi'an 710065,China)

机构地区：[1]陕西省康复医院,陕西西安710065

出　　处：《临床医学研究与实践》2023年第20期77-80,共4页Clinical Research and Practice

摘　　要：目的分析小切口白内障囊外摘除术治疗硬核白内障患者的有效性与安全性。方法根据手术治疗方案差异将我院2020年1月至12月收治的80例硬核白内障患者分为常规组(40例,常规切口白内障囊外摘除术)和观察组(40例,小切口白内障囊外摘除术)。比较两组的手术效果。结果术后1个月,观察组的术眼眼角膜内皮细胞密度显著大于常规组,细胞平均面积、角膜厚度显著小于常规组(P<0.05)。术后1个月,观察组的泪膜破裂时间(BUT)显著长于常规组,基础泪液分泌试验(SⅠT)和主观干眼症状问卷评分(SDES)显著低于常规组(P<0.05)。术后3 d,观察组的超氧化物歧化酶(SOD)、丙二醛(MDA)、转化生长因子-β_(1)(TGF-β_(1))和肿瘤坏死因子-α(TNF-α)水平显著低于常规组(P<0.05)。观察组术后3个月内的角膜水肿、囊膜混浊、纤维素样渗出、晶体表面色素沉着、虹膜粘连、黄斑囊样水肿发生率均显著低于常规组(P<0.05)。结论小切口白内障囊外摘除术治疗硬核白内障可取得理想手术效果,安全性较高。Objective To analyze the efficacy and safety of small-incision extracapsular cataract extraction in the treatment of patients with hard nuclear cataract.Methods A total of 80 patients with hard nuclear cataract admitted in our hospital from January to December 2020 were divided into conventional group(40 cases,routine incision extracapsular cataract extraction)and observation group(40 cases,small-incision extracapsular cataract extraction)according to the difference of surgical treatment plan.The surgical effects of the two groups were compared.Results One month after surgery,the corneal endothelial cell density of the observation group was significantly greater than that of the conventional group,and the average cell area and corneal thickness were significantly smaller than those of the conventional group(P<0.05).One month after surgery,the break-up time(BUT)of the observation group was significantly longer than that of the conventional group,and the schirmerⅠtest(SⅠT)and the Score of Dry Eye Symptoms(SDES)were significantly lower than those of the conventional group(P<0.05).At 3 d after surgery,the levels of superoxide dismutase(SOD),malondialdehyde(MDA),transforming growth factor-β_(1)(TGF-β_(1))and tumor necrosis factor-α(TNF-α)in the observation group were significantly lower than those in the conventional group(P<0.05).The incidences of corneal edema,capsule opacity,fibrinoid exudation,pigmentation on the surface of the crystal,iris adhesion and cystoid macular edema in the observation group within 3 months after surgery were significantly lower than those in the conventional group(P<0.05).Conclusion Small-incision extracapsular cataract extraction in the treatment of hard nuclear cataract can achieve ideal surgical results and has high safety.

关 键 词：硬核白内障 白内障囊外摘除术 常规切口 小切口 

分 类 号：R779.66[医药卫生—眼科]