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作 者:Zhaodi WANG Xuan LU Yunmei YANG Yuanqiang LU
机构地区:[1]DepartmentofGeriatricandEmergency Medicine,theFirst Affiliated Hospital.Zhejiang University Schoolof Medicine,Hangzhou310003 China [2]Key Laboratoryfor Diagnosis and Treatment of Aging and Physic-chemical Injury Diseases of Zhejiang Province,Hangzhou310003.China
出 处:《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2023年第6期539-542,共4页浙江大学学报(英文版)B辑(生物医学与生物技术)
基 金:by the Ethics Committee of the First Affiliated Hospital,Zhejiang University School of Medicine(StudyID:20230163).
摘 要:Epstein-Barr virus(EBV),a double-stranded DNA virus with an envelope,is a ubiquitous pathogen that is prevalent in humans,although most people who contract it do not develop symptoms(Kerr,2019).While the primary cells EBV attacks are epithelial cells and B lymphocytes,its target range expands to a variety of cell types in immunodeficient hosts.Serological change occurs in 90%of infected patients.Therefore,immunoglobulin M(IgM)and IgG,serologically reactive to viral capsid antigens,are reliable biomarkers for the detection of acute and chronic EBV infections(Cohen,2000).Symptoms of EBV infection vary according to age and immune status.
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