Transportation of citrinin is regulated by the CtnC gene in the medicinal fungus Monascus purpureus  

作　　者：Yanling GUI Guangfu TANG Haiqiao MAN Jiao WANG Jie HAN Jiehong ZHAO 

机构地区：[1]Key Lab of Pharmacognostics of Guizhou Province,Guizhou University of Traditional Chinese Medicine,Guiyang 550025,China [2]College of Pharmacy,Guizhou University of Traditional Chinese Medicine,Guiyang 550025,China

出　　处：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2023年第6期543-548,共6页浙江大学学报（英文版）B辑（生物医学与生物技术）

基　　金：supported by the Science and Technology Planning Project of Guizhou Province(No.2019-2776);the National Natural Science Foundation of China(No.81960692).

摘　　要：Monascus is one of the most essential microbial resources in China,with thousands of years of history.Modern science has proved that Monascus can produce pigment,ergosterol,monacolin K,-aminobutyric acid,and other functionally active substances.Currently,Monascus is used to produce a variety of foods,health products,and pharmaceuticals,and its pigments are widely used as food additives.However,Monascus also makes a harmful polyketide component called citrinin in the fermentation process;citrinin has toxic effects on the kidneys such as teratogenicity,carcinogenicity,and mutagenicity(Gong et al.,2019).The presence of citrinin renders Monascus and its products potentially hazardous,which has led many countries to set limits and standards on citrinin content.

关 键 词：RENDER MONASCUS FUNGUS 

分 类 号：TP212[自动化与计算机技术—检测技术与自动化装置]