Rh-Catalyzed diastereoselective addition of arylboronic acids to α-keto N-tert-butanesulfinyl aldimines: synthesis of α-amino ketones  

作　　者：Cece Wang Lu Zhou Jian Qiu Kai Yang Qiuling Song 

机构地区：[1]Key Laboratory of Molecule Synthesis and Function Discovery,Fujian Province University,College of Chemistry at Fuzhou University,Fuzhou,Fujian,350108,China [2]Institute of Next Generation Matter Transformation,College of Materials Science Engineering at Huaqiao University,668 Jimei Boulevard,Xiamen,Fujian,361021,China

出　　处：《Organic Chemistry Frontiers》2022年第4期1016-1022,共7页有机化学前沿（英文）

基　　金：Financial support from the National Natural Science Foundation of China(21772046,2193103 and 22001038);Fuzhou University(510578)is gratefully acknowledged.

摘　　要：Herein we present a diastereoselective addition of arylboronic acids toα-keto N-tert-butanesulfinyl aldi-mines catalyzed by a Rh(I)catalyst.This reaction provides a practical method to obtain valuable chiralα-amino ketones with excellent diastereoselectivity,featuring operational simplicity,mild reaction con-ditions and a broad substrate scope.

关 键 词：catalyst boron STEREOSELECTIVE 

分 类 号：O62[理学—有机化学]