人工真皮在皮肤恶性肿瘤切除术后创面修复中的临床价值  

The efficacy of artificial dermis for wound repair after resection of cutaneous malignant tumors

作　　者：李建建 缪永锐 李玉梅[1] 李展宇[1] 马寒 LI Jianjian;MIO Wengloi;LI Yumei;LI Zhanyu;MA Han(Fifth Affiliated Hospital,Sun Yat-sen University,Zhuhai 519000,China)

机构地区：[1]中山大学附属第五医院,广东珠海519000

出　　处：《皮肤性病诊疗学杂志》2023年第3期227-231,共5页Journal of Diagnosis and Therapy on Dermato-venereology

摘　　要：目的探讨人工真皮在皮肤恶性肿瘤切除术后创面修复的临床疗效。方法收集中山大学附属第五医院住院的难以用皮瓣修复或基础疾病较多的皮肤恶性肿瘤患者25例,包括基底细胞癌16例、皮肤鳞状细胞癌7例、隆突性皮肤纤维肉瘤2例,均采用Mohs显微外科手术切除肿瘤,术后创面使用人工真皮覆盖,观察术后恢复效果。结果25例患者均完成修复。23例(92.00%)患者术后1~2个月创面愈合,轻度疤痕增生;3个月后所有患者伤口都愈合。半年后随访,疤痕轻度增生。结论人工真皮能有效覆盖皮肤恶性肿瘤切除术后创面,操作简单;创面愈合后仅轻度疤痕增生,总体效果较好。Objective To investigate the efficacy of artificial dermis for wound repair after resection of cutaneous malignant tumors.Methods Twenty-five inpatients with cutaneous malignant tumors,including basal cell carcinoma(16 cases),squamous cell carcinoma(7 cases),and dermatofibrosarcoma protuberans(2 cases),were enrolled from our hospital.Among these patients,either their wound could not be repaired with traditional skin flaps or they had underlying medical conditions.Tumors were removed by Mohs microsurgery,followed by placement of artificial dermis on the wound.Results Complete wound repair was observed in all patients.Of the 25 patients,23 cases(92.00%)showed complete wound healing with mild hypertrophic scar within 1-2 months post-surgery.All wounds were healed within 3 months after the surgery.Only mild hypertrophic scars were observed during six-month follow-up.Conclusions Artificial dermis is effective for wound repair after resection of cutaneous malignant tumors,with mild hypertrophic scar,and is easy to use.

关 键 词：人工真皮 皮肤恶性肿瘤 创面修复 

分 类 号：R739.5[医药卫生—肿瘤]