Impact of COVID-19 in individuals with and without pre-existent digestive disorders with a particular focus on elderly patients  

作　　者：Alfredo Papa Marcello Covino Sara Sofia De Lucia Angelo Del Gaudio Marcello Fiorani Giorgia Polito Carlo Romano Settanni Andrea Piccioni Francesco Franceschi Antonio Gasbarrini 

机构地区：[1]CEMAD,Center for Diagnosis and Treatment of Digestive Diseases,Fondazione Policlinico Universitario A.Gemelli,IRCCS,Roma 00168,Italy [2]CEMAD,UniversitàCattolica del Sacro Cuore,Roma 00168,Italy [3]Department of Emergency,UniversitàCattolica del Sacro Cuore-Fondazione Policlinico Universitario A.Gemelli,IRCCS,Rome 00168,Italy [4]Emergency Medicine,UniversitàCattolica del Sacro Cuore,Roma 00168,Italy [5]Digestive Disease Center,Fondazione Policlinico Universitario A.Gemelli IRCCS-UniversitàCattolica del Sacro Cuore,Rome 00168,Italy [6]Department of Emergency,Fondazione Policlinico Universitario A.Gemelli,IRCCS,Roma 00168,Italy [7]Department of Emergency,UniversitàCattolica del Sacro Cuore,Roma 00168,Italy

出　　处：《World Journal of Gastroenterology》2023年第26期4099-4119,共21页世界胃肠病学杂志（英文版）

摘　　要：Coronavirus disease 2019(COVID-19)has several extrapulmonary symptoms.Gastrointestinal(GI)symptoms are among the most frequent clinical manifestations of COVID-19,with severe consequences reported in elderly patients.Furthermore,the impact of COVID-19 on patients with pre-existing digestive diseases still needs to be fully elucidated,particularly in the older population.This review aimed to investigate the impact of COVID-19 on the GI tract,liver,and pancreas in individuals with and without previous digestive diseases,with a particular focus on the elderly,highlighting the distinctive characteristics observed in this population.Finally,the effectiveness and adverse events of the anti-COVID-19 vaccination in patients with digestive disorders and the peculiarities found in the elderly are discussed.

关 键 词：COVID-19 ELDERLY Inflammatory bowel disease Liver disease CIRRHOSIS Pancreatic disease 

分 类 号：R563.1[医药卫生—呼吸系统] R57[医药卫生—内科学]