精神分裂症超高危人群保护性因素和早期干预的研究进展  

Progress in the study of protective factors and early intervention in individuals at ultra-high risk for schizophrenia

作　　者：杨学智 苏映 马贞玉[1] 费立鹏[3] Yang Xuezhi;Su Ying;Ma Zhenyu;Michael R.Phillips(School of Public Health,Guangxi Medical University,Nanning 530021,China;Department of Substance Dependence,Nanning Fifth People's Hospital,Nanning 530001,China;Crisis Intervention Research Center,Shanghai Mental Health Center,Shanghai Jiao Tong University School of Medicine,Shanghai 201108,China)

机构地区：[1]广西医科大学公共卫生学院,南宁530021 [2]广西南宁市第五人民医院物质依赖科,南宁530001 [3]上海交通大学医学院附属上海精神卫生中心危机干预研究室,上海201108

出　　处：《广西医科大学学报》2023年第5期709-715,共7页Journal of Guangxi Medical University

基　　金：美国国立卫生研究院基金资助项目(No.MH108385 R01)。

摘　　要：精神分裂症前驱期表现包括感知、思维、言语、行为等多方面障碍,这是大多数精神分裂症在首次发病前就存在的症状,通过增强精神分裂症超高危人群的保护性因素和早期干预可以延缓精神分裂症的发作。近年来,在遗传学、社会、心理等领域对精神分裂症超高危人群的研究取得了重要进展。本文对上述领域进行回顾,为寻找更多精神分裂症超高危人群的保护性因素和恰当的早期干预方案提供依据。The prodromal phase of schizophrenia is characterized by various impairments in perception,thinking,speech,behavior and other aspects,which commonly occur before the first onset of most cases of schizophrenia.The onset of schizophrenia can be delayed by enhancing protective factors and providing early intervention in individuals at ultra-high risk for schizophrenia.In recent years,significant progress has been made in the genetic,social,psychological and other fields in the study of individuals at ultra-high risk for schizophrenia.This article reviews the above fields with the goal of providing a basis for finding more specific protective factors and appropriate early intervention programs for individuals at ultra-high risk for schizophrenia.

关 键 词：精神分裂症超高危人群 保护性因素 早期干预 

分 类 号：R749.3[医药卫生—神经病学与精神病学]