二维应变参数结合组织多普勒Tei指数在酒精所致精神和行为障碍患者左心功能的应用研究  

Application of Two-dimensional Strain Parameters Combined with Tissue Doppler Tei Index in Left Ventricular Function in Patients with Alcohol-induced Mental and Behavioral Disorders

作　　者：刘小冲 谷孝艳[2] 卜力[1] 艾妍 周京燕 张童洁 何怡华[2] Liu Xiaochong;Gu Xiaoyan;Bu Li;Ai Yan;Zhou Jingyan;Zhang Tongjie;He Yihua(Department of Function Examination,Beijing Anding Hospital,Capital Medical University,Beijing 100020,China;Department of Ultrasound,Beijing Anzhen Hospital,Capital Medical University,Beijing 100029,China)

机构地区：[1]首都医科大学附属北京安定医院功能检查科,北京市100020 [2]首都医科大学附属北京安贞医院超声科,北京市100029

出　　处：《中国超声医学杂志》2023年第6期661-664,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的探讨二维应变及应变率结合组织多普勒Tei指数在酒精所致精神和行为障碍患者左心功能的应用价值。方法回顾性分析收治的55例酒精所致精神和行为障碍患者的临床及超声多普勒资料,同时选择同期110例正常者作为对照组。观察并比较两组受检者心脏形态、组织多普勒Tei指数及心肌应变、应变率等相关心功能指标。结果观察组患者心腔增大以左心房、左心房室为主,左心室射血分数(LVEF)、左心室缩短分数(LVFS)、E峰与A峰比值(E/A)均低于对照组,差异有统计学意义(P<0.05);二尖瓣环室间隔处、二尖瓣环侧壁处射血时间(ET)均低于对照组,等容收缩时间(ICT)+等容舒张时间(IRT)、Tei指数均高于对照组,差异有统计学意义(P<0.01);左心室GLS及各节段心肌S、SR均明显低于对照组,差异有统计学意义(P<0.01)。结论采用二维心肌应变参数结合组织多普勒Tei指数对酒精所致精神和行为障碍患者的心功能进行早期心脏超声监测,可及早发现心功能异常,在心肌损害早期引起临床足够的重视,为临床诊断及治疗提供相应指导。Objective To explore the application value of two-dimensional strain and strain rate combined with tissue Doppler Tei index in left ventricular function in patients with alcohol-induced mental and behavioral disorders.Methods The clinical and ultrasonic Doppler data of 55 patients with alcohol-induced mental and behavioral disorders admitted to Beijing Anding Hospital of Capital Medical University were retrospectively analyzed,and 11o health people in the same period were selected as the control group.Cardiac morphology,tissue Doppler Tei index,myocardial strain,strain rate and other related functional indexes were observed and compared between the two groups.Results The cardiac cavity enlargement in the observation group was mainly in the left atrium and ventricle,and left ventricular ejection fraction(LVEF),left ventricular shortening fraction(LVFS)and E/A ratio were lower than those in the control group,with statistical significance(P<0.05).Ejection time(ET)at the ventricular septum of mitral annulus,and lateral wall of mitral annulus were lower than those in the control group,and isovolumic contraction time(ICT)and isovolumic relaxation time(IRT)and Tei index were higher than those in the control group,the difference was statistically significant(P<0.O1).The left ventricular global longitudinal strain(GLS)and myocardial strain and strain rate in each segment were significantly lower than those in the control group,with statistical significance(P<O.O1).Conclusions Using two-dimensional myocardial strain parameters combined with tissue Doppler Tei index to monitor the cardiac function of patients with alcohol-induced mental and behavioral disorders by early cardiac ultrasound can lead to early occurrence of cardiac dysfunction,which can cause sufficient clinical attention in the early stage of myocardial damage,and provide corresponding guidance for clinical diagnosis and treatment.

关 键 词：酒精所致精神和行为障碍 心肌应变 TEI指数 心功能 

分 类 号：R749.62[医药卫生—神经病学与精神病学]