螺旋霉素的电化学检测研究  

Study on electrochemical detection of spiramycin

作　　者：秦洪伟 刘妍[2] QIN Hong-wei;LIU Yan(School of Textile,Changzhou Vocational Institute of Textile and Garment,Changzhou 213164,China;College of Chemistry and Materials Engineering,Bohai University,Jinzhou 121013,China)

机构地区：[1]常州纺织服装职业技术学院纺织学院,江苏常州213164 [2]渤海大学化学与材料工程学院,辽宁锦州121013

出　　处：《现代化工》2023年第6期245-248,共4页Modern Chemical Industry

基　　金：国家自然科学基金项目(41602351);辽宁省教育厅2021年度科学研究经费项目(面上项目)(LJKZ1031)。

摘　　要：通过恒电位还原氧化石墨烯的方法制备电化学还原氧化石墨烯修饰电极(rGO/GCE),再结合浸渍法制备出电化学还原氧化石墨烯纳米银复合修饰电极(rGO-AgNPs/GCE)。考察了螺旋霉素(SPY)在rGO-AgNPs/GCE上的电化学响应情况,并对修饰量、电还原时间、浸渍时间、支持电解质种类及酸碱度等实验条件进行优化。结果显示,在2.0×10^(-6)~1.0×10^(-4)mol/L浓度范围内,SPY氧化峰电流与其浓度呈显著的线性关系,线性方程为I_(p)=0.5285c+26.085,r=0.9973,检测下限为4.0×10^(-7)mol/L。稳定性、可重复性和回收率实验取得令人满意的结果。Electrochemical-reduced graphene oxide modified electrode(rGO/GCE)is prepared through potentiostatic reduction of graphene oxide,and used to prepare electrochemical-reduced graphene oxide-nano silver composite modified electrode(rGO-AgNPs/GCE)by impregnation method.The electrochemical response of spiramycin on rGO-AgNPs/GCE is investigated,and a series of experimental conditions are optimized,including the amount of modification,impregnation time,electric reduction time,type and pH of supporting electrolyte.It is shown that the oxidation peak current of spiramycin has a significant linear relationship with its concentration in the range of 2.0×10^(-6)-1.0×10^(-4)mol·L^(-1),the linear equation is I_(p)=0.5285c+26.085,and the correlation coefficient is 0.9973,and the lowest detection limit is 4.0×10^(-7)mol·L^(-1).It also shows a satisfied result in stability,repeatability and recovery.

关 键 词：纳米银 电化学还原氧化石墨烯 电化学检测 螺旋霉素 

分 类 号：X132[环境科学与工程—环境科学] O657.1[理学—分析化学]