水胶体敷料联合贝复新在结直肠癌放射性皮炎早期临床干预中的效果  

Effect of hydrocolloid dressing combined with Beifuxin in the early clinical intervention of radiodermatitis in colorectal cancer

作　　者：邹玉芬[1] 廖光晶[1] 王素贤[2] 华媚[1] 王春梅[3] 涂福平[1] 张华香[1] 陈丽英[1] ZOU Yufen;LIAO Guangjing;WANG Suxian;HUA Mei;WANG Chunmei;TU Fuping;ZHANG Huaxiang;CHEN Liying(Department of Oncology,the First Affiliated Hospital of Gannan Medical College,Ganzhou,Jiangxi 341000,China;Department of Vascular surgery,the First Affiliated Hospital of Gannan Medical College,Ganzhou,Jiangxi 341000,China;Department of Pharmacy Intravenous Admixture Services,the First Affiliated Hospital of Gannan Medical College,Ganzhou,Jiangxi 341000,China)

机构地区：[1]赣南医学院第一附属医院肿瘤科,江西赣州341000 [2]赣南医学院第一附属医院血管外科,江西赣州341000 [3]赣南医学院第一附属医院静脉用药调配中心,江西赣州341000

出　　处：《检验医学与临床》2023年第14期2028-2031,共4页Laboratory Medicine and Clinic

基　　金：江西省卫生健康委科技计划项目(202310792)。

摘　　要：目的探讨水胶体敷料联合贝复新在结直肠癌放射性皮炎早期临床干预中的效果。方法选取2021年2月至2022年11月该院收治的68例结直肠癌放射性皮炎患者作为研究对象,采用电脑随机法分为对照组和观察组,每组各34例。对照组患者采用常规护理干预,观察组患者采用水胶体敷料联合贝复新干预。比较两组患者的临床疗效、症状评分、创面愈合情况、生活质量。结果观察组患者临床疗效(97.06%)高于对照组(82.35%),差异有统计学意义(P<0.05);观察组患者干预后15 d症状评分低于对照组,差异有统计学意义(P<0.05);观察组患者平均维护次数少于对照组,差异有统计学意义(P<0.05);观察组患者起效时间及治愈时间均短于对照组,差异均有统计学意义(P<0.05);观察组患者每项生活质量评分均高于对照组,差异均有统计学意义(P<0.05)。结论对结直肠癌放射性皮炎患者实施水胶体敷料联合贝复新进行早期干预可明显促进患者创面愈合,减轻炎症反应,改善其生活质量。Objective To investigate the effect of hydrocolloid dressing combined with Beifuxin in the early clinical intervention of radiodermatitis in colorectal cancer.Methods A total of 68 patients with radiodermatitis of colorectal cancer admitted to our hospital from February 2021 to November 2022 were selected as research objects and divided into control group and observation group by computer randomized method,with 34 cases in each group.Patients in control group received routine nursing intervention,while patients in observation group received hydrocolloid dressing combined with Beifuxin intervention.The clinical efficacy,symptom score,wound healing and quality of life were compared between the 2 groups.Results The clinical efficacy of observation group(97.06%)was higher than that of control group(82.35%),and the difference was statistically significant(P<0.05).The symptom score of observation group was lower than that of control group after 15 days intervention,and the difference was statistically significant(P<0.05).The average maintenance times in patients of observation group were less than those of control group,and the difference was statistically significant(P<0.05).The onset time and cure time of observation group were shorter than those of control group,and the differences were statistically significant(P<0.05).The each quality of life score of observation group was higher than that of control group,and the difference was statistically significant(P<0.05).Conclusion Early intervention of hydrocolloid dressing combined with Beifuxin of radiodermatitis in colorectal cancer in patients can significantly promote wound healing,reduce inflammatory response,and improve their quality of life.

关 键 词：结直肠癌放射性皮炎 水胶体敷料 贝复新 炎症反应 愈合时间 

分 类 号：R735.3[医药卫生—肿瘤]