高脂血症是头颅MRI指导的静脉溶栓脑出血的高危因素  

Hyperlipidemia is a risk factor of cerebral hemorrhage after intravenous thrombolysis guided with cranial MRI

作　　者：李敏 李锦师[1] 陈娟[1] 陆练军[1] 沈健[1] 白青科[1] Li Min;Li Jinshi;Chen Juan;Lu Lianjun;Shen Jian;Bai Qingke(Department of Neurology,the Shanghai Pudong New Area People's Hospital,Shanghai 201200,China)

机构地区：[1]上海市浦东新区人民医院神经内科,上海201200

出　　处：《脑与神经疾病杂志》2023年第7期438-441,共4页Journal of Brain and Nervous Diseases

基　　金：上海市浦东新区卫生健康委员会卫生科技项目(PW2021A-60)。

摘　　要：目的评估头颅MRI指导的静脉溶栓中,性别、年龄、吸烟史、饮酒史、MRI、高脂血症、醒后卒中、短暂性脑缺血发作起病的脑梗死与溶栓后脑出血(ICH)有无关系。方法 根据静脉溶栓后头颅CT有无ICH分为ICH组和非ICH组,分析两组患者之间性别等因素差异有统计学意义。结果 两组之间高脂血症有明显差异(P=0.025)。结论 高脂血症与头颅MRI指导的静脉溶栓患者ICH相关,而性别等因素与溶栓后ICH无关。Objective To assess the association of the factors such as gender,age,smoking history,drinking history,MRI,hyperlipidemia,wake-up stroke,transient ischemic attack-like stroke with cerebral hemorrhage after intravenous thrombolysis(IVT).Methods According to the result of cerebral CT after IVT,the patients were subdivided into intracerebral hemorrhage(ICH)group and noncerebral hemorrhage group.And then analyze whether there were statistical difference between the two groups,on the respects of gender,age,smoking history,drinking history,MRI,hyperlipidemia wake-up stroke and transient ischemic attack-like stroke.Results There is statistical difference on the aspect of hyperlipidemia between the two groups(P=0.025).Conclusion There is association with hyperlipidemia and ICH after IVT guided with cranial MRI.While there is no association with gender,age,smoking history,drinking history,MRI,wake-up stroke and transient ischemic attack-like stroke between the two groups.

关 键 词：头颅MRI指导的静脉溶栓 脑出血 高脂血症 醒后卒中 短暂性脑缺血发作起病的脑梗死 

分 类 号：R743.32[医药卫生—神经病学与精神病学]