白内障手法碎核折叠人工晶状体植入术治疗硬核白内障疗效及对患者角膜内皮细胞损伤的影响  

Effect of cataract manipulation with nuclear fragmentation and folding intraocular lens implantation for hard nucleus cataract and its effect on corneal endothelial cell injury

作　　者：张建成[1] ZHANG Jian-cheng(Department of Ophthalmology,Nanyang First People's Hospital,Nanyang 473000,China)

机构地区：[1]南阳市第一人民医院眼科,河南南阳473000

出　　处：《黑龙江医药科学》2023年第3期69-71,共3页Heilongjiang Medicine and Pharmacy

摘　　要：目的:探讨白内障手法碎核折叠人工晶状体植入术治疗硬核白内障疗效及对患者角膜内皮细胞损伤的影响。方法:选取本院2020-05~2021-12收治的硬核白内障患者60例(均为单眼),按照不同手术方案分为观察组(n=32)和对照组(n=28)。对照组患者给予超声乳化白内障摘除术治疗,观察组患者给予白内障手法碎核折叠人工晶状体植入术治疗,比较术前、术后1天、1周和1个月视力情况、术前和术后2h、12h、24h、1周眼压变化情况、角膜内皮细胞损伤程度。结果:观察组治疗效果明显优于对照组(P<0.05)。术后1个月、3个月观察组角膜内皮细胞密度明显低于对照组(P<0.05),而六角形细胞比率差异不大(P>0.05)。结论:白内障手法碎核折叠人工晶状体植入术治疗硬核白内障疗效较好,对硬核白内障患者角膜内皮细胞损伤较大,但是角膜内皮细胞丢失率不大。Objective:To investigate the curative effect of cataract manipulative nuclear fragmentation and intraocular lens implantation in the treatment of hard nucleus cataract and the effect on corneal endothelial cell injury.Methods:A total of 60 patients with hard nucleus cataract(all monocular)admitted to our hospital from May 2020 to December 2021 were selected and divided into observation group(n=32)and control group(n=28)according to different surgical plans.Patients in the control group were treated with phacoemulsification cataract extraction,and patients in the observation group were treated with manual nuclear fragmentation intraocular lens implantation.The visual acuity before,one day,one week and one month after surgery,intraocular pressure changes before and at 2h,12h,24h and one week after surgery,and the damage degree of corneal endothelial cells were compared.Results:The therapeutic effect of observation group was significantly better than control group(P<0.05).The density of corneal endothelial cells in the observation group was significantly lower than that in the control group at 1 and 3 months after operation(P<0.05),while the ratio of hexagonal cells was not significantly different(P>0.05).Conclusion:Manual nuclear fragmentation and folding cataract intraocular lens implantation is effective in the treatment of hard nucleus cataract.The damage of corneal endothelial cells in patients with hard nucleus cataract is large,but the loss rate of corneal endothelial cells is small.

关 键 词：硬核白内障 白内障手法碎核 折叠 人工晶状体 角膜内皮细胞 

分 类 号：R776.1[医药卫生—眼科]