水苏糖对Ⅱ型糖尿病及其部分并发症缓解作用的研究进展  

Research progress on relieving effect of stachyose on type Ⅱ diabetes mellitus and some of its complications

作　　者：梁鑫富 董庆亮 高加涛 LIANG Xinfu;DONG Qingliang;GAO Jiatao(College of Light Industry and Food Engineering,Guangxi University,Nanning 530000,China;Food Engineering College,Beibu Gulf University,Qinzhou 535000,China;Junshi Tongkang Technology Development(Beijing)Co.Ltd.,Beijing 100101,China)

机构地区：[1]广西大学轻工与食品工程学院,广西南宁530000 [2]北部湾大学食品工程学院,广西钦州535000 [3]菌食同康科技发展(北京)有限公司,北京100101

出　　处：《食品与发酵工业》2023年第14期330-337,共8页Food and Fermentation Industries

基　　金：广西科技厅科技基地和人才专项(桂科AD20159019);广西教育厅高校科研项目(2019KY0439);2019年北部湾大学高层次人才科研启动经费项目(2019KYQD10)。

摘　　要：Ⅱ型糖尿病(type 2 diabetes mellitus, T2DM)是一种患者数量逐年增加的流行性慢性代谢疾病,因其代谢功能受损等因素而普遍会引起多种并发症,严重威胁人类身体健康。水苏糖作为传统中药地黄中含量最高的寡糖,现代研究已表明,它也具有降血糖的功能。而且水苏糖还能通过增殖肠道益生菌等方式对人体产生多种积极效应,可以改善T2DM的并发症,有成为新型天然降糖药的潜力。该文阐述了水苏糖与T2DM的研究进展及潜在的作用机制,以期为治疗T2DM的水苏糖产品研发及相关治疗等提供理论参考。Type 2 diabetes mellitus(T2DM)is an epidemic chronic metabolic disease with an increasing number of patients year by year.Due to factors such as impaired metabolic function,it can generally cause a variety of complications,which seriously threatens human health.As the oligosaccharide with the highest content in traditional Chinese medicine Rehmannia glutinosa,modern research has shown that it also has the function of lowering blood sugar.Moreover,stachyose can also have a variety of positive effects on the human body by proliferating intestinal probiotics,which can improve the complications of T2DM,and has the potential to become a new natural hypoglycemic drug.This article expounds the research progress and potential mechanism of stachyose and T2DM,in order to provide a theoretical reference for the development of stachyose products for the treatment of T2DM and related treatments.

关 键 词：水苏糖 Ⅱ型糖尿病 降血糖 肠道菌群 作用机制 

分 类 号：R587.1[医药卫生—内分泌]