基于定量CT分析肝脂肪变性与中医体质及代谢指标的相关性  

Investigation of the Correlation between Hepatic Steatosis and TCM Constitution and Metabolic Indexes Based on Quantitative CT

作　　者：梁玉龙 郭翔宇[1] 陈涛 富斌[1] 吴梦玮[1] 郭鹏德[1] LIANG Yu-long;GUO Xiang-yu;CHEN Tao;FU Bin;WU Meng-wei;GUO Peng-de(Dongfang Hospital of Beijing University of Chinese Medicine,Beijing 100078,China)

机构地区：[1]北京中医药大学东方医院,北京100078

出　　处：《中国CT和MRI杂志》2023年第7期112-114,共3页Chinese Journal of CT and MRI

基　　金：北京慢性病防治与健康教育研究会(MB20220301)。

摘　　要：目的定量分析体检人群肝脂肪变性与中医体质、BMI及实验室代谢指标的关系。方法使用定量CT(quantitative computerized tomography,QCT)测量肝脏脂肪体积百分比(Fat%QCT),纳入肝脂肪变性程度≥5%的体检受试者158例。收集临床资料及中医体质结果,分析受试者的中医体质分布特点,观察Fat%QCT与中医体质、BMI及实验室代谢指标的相关性。结果158例受试者的平均Fat%QCT为10.3±6.8%;肥胖组Fat%QCT值显著高于未超重组(11.7±4.1%VS 8.9±6.5%),糖尿病组Fat%QQCT值显著高于血糖正常组(14.2±11.4%VS 9.7±6.2%),两组组内均具有统计学意义。在中医体质方面,158例受试者中兼杂偏颇体质共124例(78.5%),前3位分别是痰湿质+湿热质、气虚质+痰湿质和气虚质+湿热质;单纯体质31例(19.6%),前3位分别是气虚质、湿热质和痰湿质。相关分析显示:受试者Fat%QCT与BMI、血糖及痰湿质显著正相关(rs=0.35、0.30、0.18,P<0.05)。结论定量CT可以稳定评估脂肪肝,Fat%QCT值与BMI、血糖和中医体质相关。Objective To investigate the correlation between hepatic steatosis and TCM constitution and laboratory metabolic indexes in quantitative way.Methods Quantitative computerized tomography(QCT)is used to measure the liver fat volume percentage(Fat%QCT),158 cases from check-up crowd whose hepatic steatosis degree was 5%or more were involved.Collecting clinical data and TCM constitution results,analyzing the characteristics of TCM constitution distribution of the subjects and observing the correlation between Fat%QCT and TCM constitution,BMI and laboratory metabolic indexes.Results The mean Fat%QCT of 158 subjects was 10.3±6.8%.Fat%QCT of the obesity group was significantly higher than that of the non-hyperglycemic group(11.7±4.1%VS8.9±6.5%),and the Fat%QCT of the diabetes group was significantly higher than that of the normal blood glucose group(14.2±11.4%VS9.7±6.2%),which showed statistical significance in both groups.In terms of TCM constitutions,124(78.5%)of the 158 fatty liver subjects had mixed constitutions,and the top 3 were phlegm-dampness+dampnessheat,qi-deficiency+phlegm-dampness and qi-deficiency+dampness-heat.There were 31 cases(19.6%)with simple constitution,and the top 3 were qi-deficiency,dampness-heat and phlegm-dampness.Correlation analysis showed that Fat%QCT was significantly positively correlated with BMI,blood glucose and phlegm-dampness(rs=0.35,0.30,0.18,P<0.05).Conclusion Quantitative CT can stably evaluate fatty liver.Fat%QCT is related to BMI,blood glucose and TCM constitution.

关 键 词：肝脂肪变性 定量CT 中医 体质 横断面研究 

分 类 号：R575.5[医药卫生—消化系统] R445.3[医药卫生—内科学] R241.9[医药卫生—临床医学]