腹膜恶性间皮瘤合并输卵管积水一例并文献复习  

Malignant Peritoneal Mesothelioma and Hydrosalpinx:A Case Report and Literature Review

作　　者：黄秋芳 路广美 刘宝琴 黎明鸾 张毅[2] HUANG Qiu-fang;LU Guang-mei;LIU Bao-qin;LI Ming-luan;ZHANG Yi(Hainan Medical University,Haikou 571199,China;Department of Reproductive Medicine,The First Affiliated Hospital of Hainan Medical College,Hainan Provincial Key Laboratory of Human Reproduction and Genetics,Haikou 570102,China)

机构地区：[1]海南医学院,海口571199 [2]海南医学院第一附属医院生殖医学科,海南省人类生殖与遗传重点实验室

出　　处：《国际生殖健康／计划生育杂志》2023年第4期296-300,共5页Journal of International Reproductive Health/Family Planning

基　　金：海南省自然科学基金(821MS135)。

摘　　要：腹膜恶性间皮瘤(malignant peritoneal mesothelioma)是一种罕见且恶性程度极高的肿瘤。该病起病隐匿,缺乏特异性临床表现、实验室指标以及影像学特征,临床医生难以早期诊断。目前腹膜恶性间皮瘤的诊断依赖于通过手术获取病变组织,进行病理学及免疫组织化学检查。报告1例海南医学院第一附属医院收治的育龄期女性患者,原发性不孕3年,因输卵管积水行腹腔镜手术发现为腹膜恶性间皮瘤。该患者无石棉接触史,病因不明确,临床表现不典型,诊断较为困难。通过对该患者的病历资料进行回顾性分析,并对既往文献进行复习,旨在探讨腹膜恶性间皮瘤的可能病因、诊断和治疗原则,加深临床医生对该病的认识,并提高诊治能力。Malignant peritoneal mesothelioma is a rare and extremely malignant tumor.It is difficult for clinicians to diagnose early for its insidious onset and lack of specific clinical manifestations,laboratory indicators and imaging characteristics.At present,the accurate diagnosis dependes on the pathological examination and immunochemistry.In this paper,we report a case of malignant peritoneal mesothelioma found by the laparoscopic surgery due to"hydrofallopian tube".This is a female patient of childbearing age who had primary infertility for 3 years.The patient had no history of asbestos exposure,unclear etiology,atypical clinical manifestations.The diagnosis of malignant peritoneal mesothelioma was very difficult before histopathological examination.We analyze retrospectively the medical records of the patient and review of the previous literature.We explore the etiology,diagnosis and treatment of malignant peritoneal mesothelioma and enhance clinicians′comprehension.

关 键 词：恶性间皮瘤 免疫组织化学 病例报告 腹膜恶性间皮瘤 输卵管积水 

分 类 号：R735.5[医药卫生—肿瘤]