生长激素型与无功能型垂体瘤患者磁共振成像下气道解剖指标的比较  

Comparison of airway anatomical indices in magnetic resonance imaging between growth hormone pituitary adenoma and nonfunctioning pituitary adenoma

作　　者：景龙年[1] 姚婧鑫 韩如泉[1] JING Longnian;YAO Jingxin;HAN Ruquan(Department of Anesthesiology,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China)

机构地区：[1]首都医科大学附属北京天坛医院麻醉科,北京100070

出　　处：《基础医学与临床》2023年第8期1275-1279,共5页Basic and Clinical Medicine

基　　金：北京市医院管理局“登峰”人才培养计划(DFL20180502);北京市科委科技计划项目(Z19110700660000)。

摘　　要：目的评估磁共振气道解剖指标在生长激素型垂体瘤患者困难气道预测的应用价值。方法回顾性分析首都医科大学附属北京天坛医院2018年12月至2022年12月全身麻醉下行垂体瘤切除手术患者的病例资料,比较生长激素型垂体瘤(GHPA组,n=81)和同期诊断为无功能垂体瘤患者(NFPA组,n=81)的头颅磁共振成像下气道解剖指标:正中矢状面图像上测量上唇前缘到悬雍垂后缘的距离(ULUD)、颈椎2/3间隙水平的舌体厚度(TT_(C2/3))、颈椎2/3间隙水平声门上气道的前后径(SAD_(C2/3))和下唇到咽后壁的距离(ULPD)等指标,分析两组指标的统计学差异。结果GHPA组的ULUD、TT_(C2/3)和ULUD明显长于NFPA组(P<0.05);垂体瘤患者术前血清GH值与TT_(C2/3)、ULPD有显著相关性(P<0.05)。结论GHPA瘤患者的头颅MRI测量所得的ULUD、TT_(C2/3)、ULPD及血清GH值可能对GHPA患者困难气道有一定的预测价值。Objective To evaluate the application of airway anatomical indices in magnetic resonance imaging(MRI)to predict difficult airways in patients with growth hormone pituitary adenoma.Methods This is a retrospective analysis for patients with pituitary adenoma excision under general anesthesia at Beijing Tiantan Hospital,Capital Medical University,from December 2018 to December 2022.Patients with growth hormone pituitary adenoma(GH group,n=81)and patients with nonfunctioning pituitary adenoma(NF group,n=81)were included.Linear distance between upper lip and uvula(ULUD),tongue thickness on the plane of cervical vertebra 2/3(TT_(C2/3)),linear distance of supraglottic airway cervical vertebra 2/3(SAD_(C2/3))and linear distance between underlip and posterior pharyngeal wall(ULPD)were measured in the median sagittal plane of head MRI.The data in the two groups were compared.Results ULUD,TT_(C2/3),and ULPD in the GH group were significantly longer than those in the NF group(P<0.05).SAD_(C2/3) was not significantly different(P>0.05).GH was confirmed to be correlated with TT_(C2/3) and ULPD.Conclusions ULUD,TT_(C2/3),ULPD found by head MRI and GH can be used as predictors of difficult airway in patients with growth hormone pituitary adenoma.

关 键 词：生长激素 垂体瘤 磁共振成像 气道解剖指标 

分 类 号：Q575.11[生物学—生物化学] R736.4[医药卫生—肿瘤] R445.2[医药卫生—临床医学]