Antitumor Effect and Molecular Mechanism of Ophiopogonin B  

作　　者：Jingchao WANG Mingxinzhi WANG Hai CHEN Quan QUAN Xichun HUANG Chenghao JIN 

机构地区：[1]College of Life Science and Biotechnology,Heilongjiang Bayi Agricultural University,Daqing 163319,China

出　　处：《Plant Diseases and Pests》2023年第3期27-29,36,共4页植物病虫害研究（英文版）

基　　金：Supported by Central Government Supports Local College Reform and Development Fund Talent Training Projects(2020GSP16);Innovation and Entrepreneurship Training Program for College Students in Heilongjiang Province(202210223048).

摘　　要：Ophiopogonin B is a kind of saponin active substance extracted and purified from Ophiopogon japonicus,and plays an antitumor role by inhibiting cancer cell adhesion,invasion and proliferation,and inducing tumor cell apoptosis and autophagy.This paper reviews recent studies on antitumor effects and molecular mechanisms of ophiopogonin B,in order to provide a theoretical basis for subsequent development and clinical application of ophiopogonin B.

关 键 词：Ophiopogonin B ANTITUMOR Cell proliferation APOPTOSIS 

分 类 号：R285[医药卫生—中药学]