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作 者:高艳珠 张子钦[1] 龙华泉[1] 丘仲柳[1] GAO Yanzhu;ZHANG Ziqin;LONG Huaquan;QIU Zhongliu(Department of Laboratory Medicine,People's Hospital of Xinhui District of Jiangmen City,Jiangmen 529100,China)
机构地区:[1]江门市新会区人民医院检验科,广东江门529100
出 处:《包头医学院学报》2023年第7期34-38,共5页Journal of Baotou Medical College
基 金:江门市科技局科研立项项目(2021YL08017)。
摘 要:目的:探讨分析磁共振成像(MRI)联合脑脊液乳酸脱氢酶(LDH)、天门冬氨酸氨基转移酶(AST)、总蛋白(TP)诊断化脓性脑膜炎的应用效果。方法:选取2019年4月-2021年3月收治的40例化脓性脑膜炎(PM组)、40例病毒性脑膜炎(VE组)以及40例因其他疾病(非中枢神经系统感染)而行脑脊液检查的患者(非脑膜炎组)为研究对象,获取患者的脑脊液指标检查结果与MRI检查结果,并进行比较分析。结果:PM组患者的MRI阳性检出率与VE组比较无差异(P>0.05);但PM组、VE组患者的MRI阳性检出率均大于非脑膜炎组(P<0.05);PM组患者的LDH、AST、TP均高于VE组、非脑膜炎组(P<0.05);PM组的LDH、AST阳性检出率均大于VE组、非脑膜炎组(P<0.05)。LDH确诊率是37.50%、AST确诊率是25.00%、TP确诊率是7.50%、MRI确诊率是100%、LDH+AST+TP+MRI确诊率是100%。结论:联合应用MRI、LDH、AST、TP诊断化脓性脑膜炎,检出阳性率高,检出准确性大,具有显著应用价值。Objective:To investigate the application value of magnetic resonance imaging(MRI)combining with cerebrospinal fluid lactate dehydrogenase(LDH),aspartate aminotransferase(AST)and total protein(TP)in the diagnosis of suppurative meningitis.Methods:Forty patients with purulent meningitis(PM group),40 patients with viral meningitis(VE group)and 40 patients underwent cerebrospinal fluid examination due to other diseases(not central nervous system infection)(Non-meningitis group)in our hospital were selected as research objects from April 2019 to March 2021.The cerebrospinal fluid examination results and MRI examination results were obtained and compared.Results:There was no difference on the positive rate of MRI examination between the PM group and the VE group(P>0.05).However,the positive rates of MRI in the PM group and VE group were higher than that in the Non-meningitis group(P<0.05).LDH,AST and TP level in the PM group were higher than those in the VE group and Non-meningitis group(P<0.05).The positive rates of LDH and AST in the PM group were higher than those in the VE group and Non-meningitis group(P<0.05).The diagnostic rates of LDH,AST,TP,MRI and LDH+AST+TP+MRI were 37.50%,25.00%,7.50%,100%,and 100% respectively.Conclusion:The combination of MRI,LDH,AST and TP in the diagnosis of suppurative meningitis has high positive rate and high accuracy,which is of significant application value.
关 键 词:化脓性脑膜炎 乳酸脱氢酶 天门冬氨酸氨基转移酶 总蛋白 磁共振成像
分 类 号:R742.9[医药卫生—神经病学与精神病学]
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