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作 者:孔欣 袁媛[2] 韩捷[2] KONG Xin;YUAN Yuan;HAN Jie(Henan University of Chinese Medicine,Zhengzhou Henan 450000;Department of Spleen,Stomach,Liver,and Gallbladder,The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou Henan 450000)
机构地区:[1]河南中医药大学,河南郑州450000 [2]河南中医药大学第一附属医院脾胃肝胆科一病区,河南郑州45000
出 处:《世界中西医结合杂志》2023年第6期1137-1140,共4页World Journal of Integrated Traditional and Western Medicine
基 金:2018年国家重点研发计划“中医药现代化研究”专项(2018YFC1705400);河南省中医药研究专项课题(2018JDZX104)。
摘 要:溃疡性结肠炎(Ulcerative colitis, UC)是消化系统的常见病,严重影响患者的生活质量,当前对于UC尚无明确认识,其繁杂的发病原因也导致临床治疗颇为棘手。运用中医学的理论证治溃疡性结肠炎是传统西药治疗的补充,更是新的方向。韩捷教授在临证中认为“太阴病湿,湿盛则濡泄;厥阴胜复,易寒易热;少阴水火相济,病则多寒”,太阴、厥阴、少阴的病理生理与溃疡性结肠炎的发病有着根本的联系:其寒热错杂、虚实同见的证机正是溃疡性结肠炎的内在机理。治疗上从健太阴渗湿止泻、补厥阴和血养肝、温少阴平调水火出发正应其病机变化,不失为临床新的实践方向。Ulcerative colitis is a common digestive system disorder that significantly affects the quality of lifeofpatients.Currently,there is no definitive understanding of this disease,and its complex etiology makes clinical treatment quite challenging.The application of traditional Chinese medicine(TCM)theory in the diagnosis and treatment of ulcerative colitis serves as a complementary approach to conventional western medicine treatment and also represents a new direction.Professor Han Jie believes in his clinical experience that“in greater yin dampness disease,exuberant dampness leads to soggy diarrhea;alternative preponderance ofreverting yinresults in cold and heat;in terms of coordination between water and fire in lesser yin,the disease features cold”.The pathological and physiological aspects of greater yin,reverting yin,and lesser yin are fundamentally connected to the onset of ulcerative colitis.The coexistence of cold and heatsyndromes,as well as the presence of deficiency and excess,represents the underlying mechanism of this disease.In terms of treatment,addressing the changes in the pathogenesis is essential.This includes resolving dampness and stopping diarrhea by strengthening greater yin,harmonizing blood and nourishing the liver by tonifying reverting yin,and regulating water and fireby warming lesser yin.These approaches represent a new clinical practice direction.
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