Concomitant functionalization of two different ketones by merging Brønsted acid catalysis and radical relay coupling  

作　　者：Leilei Wang Leiyang Lv Zhiping Li 

机构地区：[1]Key Laboratory of Advanced Light Conversion Materials and Biophotonics,Department of Chemistry,Renmin University of China,Beijing 100872,China

出　　处：《Organic Chemistry Frontiers》2022年第6期1561-1566,共6页有机化学前沿（英文）

基　　金：supported by the National Natural Science Foundation of China(22071266);the Fundamental Research Funds for the Central Universities;the Research Funds of Renmin University of China(21XNLG04).

摘　　要：n the previous literature, incorporation of functional groups at the α-position of unactivated carbonylcompounds was mainly restricted to one kind of corresponding precursor. Herein, we report the concomitant functionalization of two distinct α-C–H bonds of carbonyls integrated with unactivated olefins andtert-butyl hydroperoxide selectively and efficiently in one pot by merging Brønsted acid catalysis andradical relay coupling, which delivers an array of structurally valuable unsymmetrical peroxy 1,9-diketonesin moderate to good yields under metal-free conditions.

关 键 词：CATALYSIS COUPLING RADICAL 

分 类 号：O62[理学—有机化学]