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作 者:李京荣[1] 邢玉静[2] 曾文军[3] LI Jingrong;XING Yujing;ZENG Wenjun(Department of Stomatology,Beijing Puren Hospital,Beijing100062,China;Department of Gerontology,Beijing Puren Hospital,Beijing100062,China;Department of Internal Medicine,Beijing Puren Hospital,Beijing100062,China)
机构地区:[1]北京市普仁医院口腔科,北京100062 [2]北京市普仁医院老年科,北京100062 [3]北京市普仁医院内科,北京100062
出 处:《中国医药导报》2023年第20期146-149,共4页China Medical Herald
基 金:北京市东城区卫生科技计划项目(东卫计研[2018]-8)。
摘 要:目的 探讨老年高血压患者拔牙前后血压水平与创口愈合效果的关系。方法 选取2019年1月至2021年12月北京市普仁医院收治的115例老年高血压患者为研究对象,所有患者行拔牙治疗。统计患者拔牙后1周创口愈合情况,并依据创口愈合情况分为愈合不良组、愈合良好组。比较两组临床资料及拔牙前后收缩压及舒张压差值;分析老年高血压患者创口愈合效果的影响因素;评估拔牙前后血压水平对创口愈合效果的预测价值。结果 115例老年高血压患者拔牙后创口愈合良好94例,创口愈合不良21例。愈合不良组血清白细胞介素-6(IL-6)水平,拔牙前后收缩压、舒张压差值高于愈合良好组(P<0.05)。IL-6、拔牙前后收缩压、舒张压差值为老年高血压患者创口愈合不良的危险因素(OR=3.080、2.954、3.350,P<0.05)。拔牙前后收缩压、舒张压差值联合检测的曲线下面积高于各项单独预测(P<0.05)。结论 老年高血压患者拔牙前后血压水平与创口愈合效果相关,且拔牙前后收缩压、舒张压差值联合检测对老年高血压患者创口愈合效果的预测效能较高。Objective To investigate the relationship between blood pressure level before and after tooth extraction and wound healing in elderly patients with hypertension.Methods A total of 115 elderly patients with hypertension admitted to Beijing Puren Hospital from January 2019 to December 2021 were selected as the study objects,and all patients were treated with tooth extraction.The wound healing of patients one week after tooth extraction was counted,and they were divided into poor healing group and good healing group according to the wound healing condition.The clinical data and the difference of systolic blood pressure and diastolic blood pressure before and after tooth extraction between two groups were compared;the influencing factors of wound healing effect in elderly hypertension patients were analyzed;the predictive value of blood pressure level before and after tooth extraction for wound healing was evaluated.Results There were 94 cases of good wound healing and 21 cases of bad wound healing in 115 elderly patients with hypertension.The level of serum interleukin-6(IL-6)and the difference of systolic blood pressure and diastolic blood pressure before and after extraction in poor healing group were higher than those in good healing group(P<0.05).IL-6,the difference of systolic blood pressure and diastolic blood pressure before and after tooth extraction were risk factors for poor wound healing in elderly patients with hypertension(OR=3.080,2.954,3.350,P<0.05).The area under the curve of combined systolic blood pressure and diastolic blood pressure before and after tooth extraction was higher than that of each single prediction(P<0.05).Conclusion The blood pressure level before and after tooth extraction is related to the wound healing effect in elderly patients with hypertension,and the combined measurement of the difference of systolic blood pressure and diastolic blood pressure before and after tooth extraction can predict the wound healing effect in elderly patients with hypertension.
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