督灸疗法对阴式子宫肌瘤剔除术后患者性激素和免疫功能的影响  

Effects of Moxibustion at Governor Vessel on Sex Hormones and Immune Function in Patients After Vaginal Myomectomy

作　　者：李艳 梁元 李亚 LI Yan;LIANG Yuan;LI Ya

机构地区：[1]郑州大学附属肿瘤医院(河南省肿瘤医院),河南郑州450002

出　　处：《新中医》2023年第12期145-149,共5页New Chinese Medicine

摘　　要：目的:观察督灸疗法对阴式子宫肌瘤剔除术后患者性激素和免疫功能的影响。方法:选择120例行阴式子宫肌瘤剔除术治疗的阳虚寒凝证患者,按照随机数字表法分为观察组和对照组,每组60例。对照组术后服用米非司酮片,观察组采用米非司酮片联合督灸疗法治疗,治疗6个月。治疗前后检测2组患者的性激素[血清促卵泡激素(FSH)、雌二醇(E_(2))、黄体生成素(LH)及孕酮(P)]及细胞免疫功能指标(CD3^(+)、CD4^(+)、CD8^(+))。比较2组的临床疗效。统计术后6个月、12个月的复发情况。结果:治疗后,观察组临床疗效总有效率高于对照组(P<0.05)。2组血清FSH、E_(2)、LH、P水平均较治疗前下降(P<0.05),观察组以上4项指标水平均低于对照组(P<0.05)。2组CD3^(+)、CD4^(+)水平均较治疗前升高(P<0.05),CD8^(+)水平均较治疗前降低(P<0.05);观察组CD3^(+)、CD4^(+)水平均高于对照组(P<0.05),CD8^(+)水平低于对照组(P<0.05)。观察组12个月复发率及总复发率均低于对照组(P<0.05)。结论:督灸疗法能够有效调节阳虚寒凝型子宫肌瘤剔除术后患者的孕激素和雌激素水平,改善免疫功能,减少复发,临床疗效显著。Objective:To observe the effect of moxibustion at governor vessel on sex hormones and immune function in patients after vaginal myomectomy.Methods:A total of 120 cases of patients with vaginal myomectomy of yang deficiency and congealing cold type were selected and divided into the observation group and the control group according to the random number table method,with 60 cases in each group.After surgery,the control group was given the oral administration of Mifepristone Tablets,and the observation group was treated with Mifepristone Tablets combined with moxibustion at governor vessel.Both groups were treated for 6 months.The levels of sex hormones[follicle-stimulating hormone(FSH),estradiol(E_(2)),luteinizing hormone(LH),and progesterone(P)in serum]and cellular immune function indexes(CD3^(+),CD4^(+),CD8^(+))in the two groups were detected before and after treatment.The clinical effects in the two groups were compared.The recurrence in 6 months and 12 months after surgery was counted.Results:After treatment,the total effective rate in the observation group was higher than that in the control group(P<0.05).After treatment,the levels of sex hormones including FSH,E_(2),LH,and P in serum in the two groups were decreased when compared with those before treatment(P<0.05),and the levels of above four indexes in the observation group were lower than those in the control group(P<0.05).The levels of CD3^(+)and CD4^(+)in the two groups were increased when compared with those before treatment(P<0.05),and the levels of CD8^(+)were decreased when compared with those before treatment(P<0.05);the levels of CD3^(+)and CD4^(+)in the observation group were higher than those in the control group(P<0.05),and the level of CD8^(+)was lower than that in the control group(P<0.05).The 12-month recurrence rate and total recurrence rate in the observation group were lower than those in the control group(P<0.05).Conclusion:Moxibustion at governor vessel for patients with hysteromyoma of yang deficiency and congealing cold type after vagi

关 键 词：子宫肌瘤 阴式子宫肌瘤剔除术 阳虚寒凝证 督灸 性激素 免疫功能 复发 

分 类 号：R737.33[医药卫生—肿瘤]