聚己内酯静电纺丝纳米纤维基复合材料在口腔医学中的应用研究进展  

Advances in the application of polycaprolactone electrospun nanofiber-based hybrid biomaterials in dentistry

作　　者：冯泽华 郑凯[2,3] 徐艳[1,2,3] FENG Zehua;ZHENG Kai;XU Yan(Department of Periodontology,the Affiliated Stomatological Hospital of Nanjing Medical University,Nanjing Medical University,Nanjing 210029,China;Key Laboratory of Oral Diseases of Jiangsu Province,Nanjing Medical University,Nanjing Medical University,Nanjing 210029,China;Jiangsu Province Engineering Research Center of Stomatological Translational Medicine,Nanjing Medical University,Nanjing 210029,China)

机构地区：[1]南京医科大学附属口腔医院牙周病科,江苏南京210029 [2]南京医科大学,江苏省口腔疾病研究重点实验室,江苏南京210029 [3]南京医科大学,江苏省口腔转化医学工程研究中心,江苏南京210029

出　　处：《南京医科大学学报（自然科学版）》2023年第8期1180-1184,共5页Journal of Nanjing Medical University(Natural Sciences)

基　　金：国家自然科学基金青年基金(82101071)。

摘　　要：静电纺丝可制备出模拟细胞外基质的生物支架材料,以聚己内酯(poly-caprolactone,PCL)作为静电纺丝原料可获得良好的生物相容性,而将PCL电纺纳米纤维与无机材料组合,可以改善支架材料亲水性和机械性能,调控降解性能,增强生物矿化能力,具有良好的应用前景。文章对PCL静电纺丝纳米纤维基复合材料在口腔医学中的应用进行综述。Electrospinning can prepare bio-scaffold materials that mimic extracellular matrix,and good biocompatibility can be obtained by using poly-caprolactone(PCL)as the raw material.The combination of PCL electrospun nanofibers with inorganic materials can improve the hydrophilic and mechanical properties of scaffold materials,regulate the degradation performance and enhance the biomineralization ability,which has promising applications.In this paper,we review the application of PCL electrospun nanofiber-based hybrid biomaterials in dentistry.

关 键 词：静电纺丝 聚己内酯 无机材料 复合材料 口腔医学 

分 类 号：R78[医药卫生—口腔医学] R318[医药卫生—临床医学]