翼状胬肉术后泪膜稳定性改变的临床研究  

Clinical Study on Tear Film Stability after Pterygium Surgery

作　　者：邬羽飞 周文君[1] 吕莎[1] 张黎明 Wu Yufei;Zhou Wenjun;Lv Sha;Zhang Liming(Department of Ophthalmology,Yongchuan Hospital of Chongqing Medical University,Chongqing 402160,P.R.China)

机构地区：[1]重庆医科大学附属永川医院眼科,重庆402160

出　　处：《科学咨询》2023年第11期148-150,共3页

基　　金：重庆市永川区科学技术局自然科学基金项目(编号:Ycstc,2019nb02023)。

摘　　要：目的采用Oculus无创性眼表综合分析仪,量化分析翼状胬肉手术前后泪膜稳定性的变化情况,探讨翼状胬肉手术对干眼症的影响。方法随机选取32例(38眼)翼状胬肉患者,手术方式均采取翼状胬肉切除联合带自体角膜缘干细胞的结膜瓣移植术。分析比较患者术前及术后三个月的泪膜稳定性。结果翼状胬肉患者术后的泪河高度(TMH)和泪膜破裂时间(BUT)结果显著优于对照组患者,差异均具有统计学意义(P<0.05)。结论翼状胬肉切除联合带自体角膜缘干细胞的结膜瓣移植术能提升翼状胬肉患者的泪膜稳定性,从而有助于减轻干眼症状。Objective To analyze the changes of tear film stability before and after pterygium surgery with the Oculus non-invasive eye surface analyzer,so to investigate the influence of pterygium surgery on dry eye.MethodsThirty two patients(38 eyes)with pterygium were treated with pterygium excision and conjunctival flap transplantation with autologous limbal stem cells.The tear film function was observed before and 3 months after operation.Results The tear meniscus height(TMH)and the break-up time(BUT)were increased after pterygium surgery and the differences were statistically significant(P<0.05).ConclusionLimbal stem cell conjunctival flap autografting for pterygium can significantly relieve the dry eye symptoms through maintaining the stability of tear film function.

关 键 词：翼状胬肉 带角膜缘干细胞的结膜瓣移植术 泪膜稳定性 干眼 

分 类 号：R73[医药卫生—肿瘤]