眼底自发荧光在年龄相关性黄斑变性中的应用指南(2023)  

Guidelines for the application of the fundus autofluorescence in age-related macular degeneration(2023)

作　　者：邵毅[1] 迟玮[2] 魏雁涛[2] 《眼底自发荧光在年龄相关性黄斑变性中的应用指南(2023)》专家组 中国医药教育协会眼科影像与智能医疗专委会 国际转化医学协会眼科专委会 中国眼科影像研究专家组 Yi Shao;Wei Chi;Yan-Tao Wei;Expert Workgroup of Guidelines for the Application of the Fundus Autofluorescence in Age-related Macular Degeneration(2023);Ophthalmic Imaging and Intelligent Medicine Branch of China Medical Education Association;Ophthalmology Branch of World Association of Translational Medicine;Chinese Ophthalmic Imaging Study Groups(Department of Ophthalmology,the First Affiliated Hospital of Nanchang University,Nanchang 330006,Jiangxi Province,China;Zhongshan Ophthalmic Center,Sun Yat-Sen University,Guangzhou 510060,Guangdong Province,China;不详)

机构地区：[1]南昌大学第一附属医院眼科,中国江西省南昌市330006 [2]中山大学中山眼科中心,中国广东省广州市510060 [3]不详

出　　处：《国际眼科杂志》2023年第8期1235-1241,共7页International Eye Science

基　　金：国家自然科学基金项目(No.82160195);江西省双千计划科技创新高端人才项目(No.jxsq2023201036);江西省重大(重点)研发专项计划(No.20181BBG70004,20203BBG73059);江西省杰出青年基金项目(No.20192BCBL23020)。

摘　　要：眼底自发荧光(FAF)成像是基于视网膜色素上皮和脉络膜中的眼内源性荧光团激发的荧光进行成像的技术,荧光激发物质主要是脂褐质(LF)和黑色素。由于该无创检查技术可通过观察LF和黑色素在眼底的空间分布来反映视网膜色素上皮的功能状况,在诊断、鉴别和随访年龄相关性黄斑变性(ARMD)上具有独特优势。本指南即对FAF在ARMD不同阶段和分类上的临床应用进行规范和解读。Fundus autofluorescence(FAF)imaging is based on the fluorescence excited by the endogenous fluorophores in the retinal pigment epithelium and choroid,mainly referring to lipofuscin(LF)and melanin.The non-invasive examination method can imply the function of retinal pigment epithelium by observing the spatial distribution of LF or melanin.This technique has unique advantages in the diagnosis and differentiation of age-related macular degeneration(ARMD).This guideline is to standardize and interpret the application of FAF in different stages and classifications of ARMD.

关 键 词：眼底自发荧光 年龄相关性黄斑变性 临床应用 

分 类 号：R774.5[医药卫生—眼科]