饮食相关炎症指数构建及其在肿瘤流行病学研究中应用  

Progress on development and application of the diet-related inflammatory index in cancer epidemiological studies

作　　者：谭靖宇 李卓颖 拓嘉怡 谭玉婷[2,4] 李泓澜[2,4] 项永兵[2,4] Tan Jingyu;Li Zhuoying;Tuo Jiayi;Tan Yuting;Li Honglan;Xiang Yongbing(School of Public Health,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China;Department of Epidemiology,Shanghai Cancer Institute,Shanghai 200032,China;School of Public Health,Fudan University,Shanghai 200032,China;State Key Laboratory of Systems Medicine for Cancer,Renji Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200032,China)

机构地区：[1]上海交通大学公共卫生学院,上海200025 [2]上海市肿瘤研究所流行病学研究室,上海200032 [3]复旦大学公共卫生学院,上海200032 [4]上海交通大学医学院附属仁济医院肿瘤系统医学全国重点实验室,上海200032

出　　处：《中华流行病学杂志》2023年第7期1151-1156,共6页Chinese Journal of Epidemiology

基　　金：国家重点研发计划(2021YFC2500404,2021YFC2500405)。

摘　　要：恶性肿瘤是全球范围内的重要公共卫生问题,其造成的疾病负担日益增加。炎症被认为是肿瘤的诱发因子,与其发生有密切关系。近年来,从炎症的角度出发去探讨饮食与肿瘤等慢性病之间关系的研究逐渐受到公众和流行病学专家的关注。本文通过对流行病学研究中常见饮食相关炎症指数文献的检索,针对其构建方法及在肿瘤流行病学研究中应用进行了系统总结和归纳。首先,重点介绍了常用饮食相关炎症指数及其构建方法,例如以膳食炎症指数为代表的由文献衍生的饮食相关炎症指数,以经验性膳食炎症指数为代表的由经验衍生的饮食相关炎症指数等。其次,对目前常用的饮食相关炎症指数的相关流行病学研究进展进行了综述。最后,简要描述了文献衍生的和经验衍生的两类膳食炎症指数的特点和局限性。以期为国内恶性肿瘤等慢性病相关营养流行病学研究提供参考。Cancer is a major public health problem worldwide,causing an more serious burden of disease.Inflammation is considered a predisposing factor for cancer with close relationship with its incidence.In recent years,the public and epidemiologists has paid more attention to the association between nutrition and cancer and other chronic diseases in the perspective of inflammation.This paper summarizes the development and application of the diet-related inflammatory index in cancer epidemiological studies based on the literature retrieval of common diet-related inflammatory index.Firstly,we highlight the common diet-related inflammatory indices and their construction methods,such as the Dietary Inflammatory Index,a literature-derived diet-related inflammatory index,and the Empirical Dietary Inflammatory Index,an empirically derived diet-related inflammatory index,and so on.Secondly,the epidemiological research progress on the commonly used diet-related inflammatory indices is briefly introduced.Finally,the advantages and disadvantages of the two types of this inflammatory indices are also briefly described for the purpose of providing reference for nutrition epidemiological studies of cancer and other chronic diseases in China.

关 键 词：饮食相关炎症指数 饮食调查 炎症 肿瘤流行病学 营养流行病学 

分 类 号：R151.41[医药卫生—营养与食品卫生学] R73-31[医药卫生—公共卫生与预防医学]