宫腔镜子宫肌瘤电切术治疗子宫黏膜下肌瘤患者的疗效及对卵巢储备功能的影响探讨  

The effect of transcervical resection of myoma on submucous fibroids of uterus and its influence on ovarian reserve function

作　　者：冯益敏 FENG Yi-min(Department of Obstetrics and Gynecology,Huai'an Second People's Hospital,Huai'an 223002,China)

机构地区：[1]江苏省淮安市第二人民医院妇产科,223002

出　　处：《中国实用医药》2023年第14期52-54,共3页China Practical Medicine

摘　　要：目的探讨子宫黏膜下肌瘤患者应用宫腔镜子宫肌瘤电切术对患者卵巢储备功能影响,观察其治疗效果。方法80例子宫黏膜下肌瘤患者,按照随机数字表达法分为观察组和对照组,每组40例。对照组实施腹腔镜子宫肌瘤剔除手术治疗,观察组实施宫腔镜子宫肌瘤电切术治疗。比较两组患者手术指标(手术时间、术中出血量、术后排气时间、住院时间)、治疗前后的卵巢储备功能指标[舒张末期血流速度(EDV)、基础窦卵泡数(AFC)、卵巢收缩期峰值血流速度(PSV)、抗苗勒氏管激素(AMH)]、临床疗效。结果观察组手术时间(36.35±5.02)min、术后排气时间(12.72±3.92)h、住院时间(4.38±1.93)d均短于对照组的(41.82±5.81)min、(16.32±3.45)h、(6.45±1.55)d,术中出血量(25.31±5.92)ml少于对照组的(31.27±5.24)ml,差异均具有统计学意义(P<0.05)。治疗后,两组EDV、AFC、PSV、AMH均下降,但观察组EDV(9.98±0.73)cm/s、AFC(6.83±0.96)个、PSV(25.91±1.88)cm/s、AMH(3.95±0.67)μg/L均高于对照组的(9.21±0.71)cm/s、(6.11±0.65)个、(20.46±1.55)cm/s、(3.36±0.82)μg/L,差异均具有统计学意义(P<0.05)。观察组治疗总有效率97.50%高于对照组的85.00%,差异具有统计学意义(P<0.05)。结论对子宫黏膜下肌瘤患者采取宫腔镜子宫肌瘤电切术进行治疗,具有创伤小、恢复快的特点,可有效缩短住院时间、手术时间,且对卵巢储备功能的影响小,利于预后,可进行推广。Objective To discuss the effect of transcervical resection of myoma on ovarian reserve function in patients with submucosal fibroids,and observe its therapeutic effect.Methods A total of 80 patients with submucosal fibroids were divided into observation group and control group according to random numerical table,with 40 cases in each group.The control group was treated with laparoscopic myomectomy,while the observation group was treated with transcervical resection of myoma.Both groups were compared in terms of surgical indexes(operating time,intraoperative blood loss,postoperative exhaust time,length of hospital stay),ovarian reserve function indexes[end-diastolic velocity(EDV),antrol follicle count(AFC),peak systolic velocity(PSV),anti-Mullerian hormone(AMH)]before and after treatment,and clinical efficacy.Results The observation group had operating time of(36.35±5.02)min,postoperative exhaust time of(12.72±3.92)h and length of hospital stay of(4.38±1.93)d,which were shorter than those of(41.82±5.81)min,(16.32±3.45)h and(6.45±1.55)d in the control group;the intraoperative blood loss of(25.31±5.92)ml in the observation group was less than that of(31.27±5.24)ml in the control group;all the differences were statistically significant(P<0.05).After treatment,EDV,AFC,PSV and AMH in both groups were decreased;in the observation group,EDV was(9.98±0.73)cm/s,AFC was(6.83±0.96),PSV was(25.91±1.88)cm/s,and AMH was(3.95±0.67)μg/L,which were higher than those of(9.21±0.71)cm/s,(6.11±0.65),(20.46±1.55)cm/s,and(3.36±0.82)μg/L in the control group;all the differences were statistically significant(P<0.05).The total effective rate of 97.50%in the observation group was higher than that of 85.00%in the control group,and the difference was statistically significant(P<0.05).Conclusion For patients with submucosal fibroids,transcervical resection of myoma has the characteristics of less trauma and faster recovery,which can effectively shorten the length of hospital stay and operating time,and has less impact on ova

关 键 词：子宫黏膜下肌瘤 宫腔镜子宫肌瘤电切术 卵巢储备功能 疗效 

分 类 号：R737.33[医药卫生—肿瘤]