鼻喷右美托咪定在儿童牙病科患儿术前镇静中的应用效果分析  

Analysis of the effect of dexmedetomidine nasal spray in the preoperative sedation of children in pediatric dentistry

作　　者：李丽丽 LI Li-li(Qufu Stomatological Hospital,Jining 273100,China)

机构地区：[1]曲阜市口腔医院,273100

出　　处：《中国实用医药》2023年第14期126-129,共4页China Practical Medicine

摘　　要：目的探讨在儿童牙病科患儿术前镇静中应用鼻喷右美托咪定的效果。方法200例儿童牙病科择期行全身麻醉(全麻)下治疗的患儿,采用随机数字表法分为对照组和观察组,每组100例。对照组患儿术前镇静给予咪达唑仑口服,观察组患儿术前镇静给予右美托咪定鼻喷。比较两组患儿麻醉效果,用药前后心率、血氧饱和度、Ramsay镇静评分,术前合作与术后躁动发生情况。结果观察组患儿自主呼吸恢复时间、苏醒时间与拔管时间分别为(7.08±1.13)、(11.27±1.72)、(13.18±2.67)min,均短于对照组的(9.81±1.52)、(15.32±2.27)、(20.16±3.17)min,差异具有统计学意义(P<0.05)。两组患儿用药前及用药后10、20、30 min的心率、血氧饱和度比较,差异均无统计学意义(P>0.05)。两组患儿用药前后各时间点心率、血氧饱和度均处于正常范围内。两组患儿用药前及用药后10、20、30 min的Ramsay镇静评分比较差异无统计学意义(P>0.05);用药后10、20、30 min,两组患儿Ramsay镇静评分均高于本组用药前,差异具有统计学意义(P<0.05)。两组患儿父母分离焦虑、面罩接受程度评分满意度比较差异均无统计学意义(P>0.05);观察组患儿术后麻醉苏醒期躁动发生率为0,低于对照组的13.00%,差异具有统计学意义(P<0.05)。结论右美托咪定鼻喷应用于儿童牙病科患儿术前镇静中可取得较好的麻醉效果,有利于提高患儿的苏醒质量,且不会导致患儿术中心率、血氧饱和度等剧烈波动,镇静效果较好,苏醒期躁动发生率低,值得推广。Objective To discuss the effect of dexmedetomidine nasal spray in the preoperative sedation of children in pediatric dentistry.Methods A total of 200 children who received elective treatment under general anesthesia in pediatric dentistry were divided into a control group and an observation group according to the random numerical table,with 100 cases in each group.Children in the control group were given midazolam orally for preoperative sedation,while children in the observation group were given dexmedetomidine nasal spray for preoperative sedation.The anesthetic effect,heart rate,blood oxygen saturation and Ramsay sedation score before and after medication,preoperative cooperation and postoperative agitation were compared between the two groups.Results The recovery time of spontaneous respiration,recovery time and extubation time were(7.08±1.13),(11.27±1.72)and(13.18±2.67)min in the observation group,which were all shorter than those of(9.81±1.52),(15.32±2.27)and(20.16±3.17)min in the control group,and the differences were statistically significant(P<0.05).There were no statistically significant differences in heart rate and blood oxygen saturation between the two groups before medication and 10,20,30 min after medication(P>0.05).Heart rate and blood oxygen saturation were in the normal range at all time points before and after medication.There was no statistically significant difference between the two groups in Ramsay sedation scores before medication and 10,20,30 min after medication(P>0.05).The Ramsay sedation scores in both groups were higher than those before medication and 10,20 and 30 min after medication in this group,and the differences were statistically significant(P<0.05).The differences in parental separation anxiety and mask acceptance score were not statistically significant between the two groups(P>0.05).The incidence of agitation during anesthesia recovery was 0 in the observation group,which was lower than that of 13.00%in the control group,and the difference was statistically significa

关 键 词：鼻喷 右美托咪定 儿童牙病科 术前镇静 

分 类 号：R782.054[医药卫生—口腔医学]