胃癌转移相关基因或标志物研究进展  

Research Progress of Metastasis Related Genes in Gastric Cancer

作　　者：魏秀珍 张政杰 WEI Xiuzhen;ZHANG Zhengjie(Wuwei Liangzhou Hospital,Wuwei,Gansu 733000;The First Clinical Medical School,Gansu University of Chinese Medicine,Lanzhou,Gansu 730050)

机构地区：[1]武威市凉州医院,甘肃武威733000 [2]甘肃中医药大学第一临床医学院,甘肃兰州730050

出　　处：《智慧健康》2023年第15期75-78,共4页Smart Healthcare

摘　　要：胃癌是发生于贲门、胃底、胃体及胃窦部的恶性肿瘤,极易发生肝、肺、肾上腺、淋巴结、腹腔等脏器转移,转移性胃癌预后相对较差,总生存期仍较短。目前现有的CEA、CA199、CA724等肿瘤标志物对胃癌转移的预测作用弱,不能早期提示胃癌的转移,故寻找新的可靠的分子标志物来早期预测或发现转移非常必要。本文将对胃癌转移相关基因的研究进展进行综述。Gastric cancer is a malignant tumor that occurs in the cardia,f undus,body and antrum of the stomach,it is very easy to metastasized to the liver,lung,adrenal gland,lymph node,abdominal cavity and other organs.The prognosis of metastatic gastric cancer is relatively poor.The 5-year survival rate is only 30%.At present,the existing tumor markers such as CEA,CA199,CA724 have weak predictive effect on gastric cancer metastasis,and cannot early indicate the metastasis of gastric cancer.Therefore,it is necessary to find new and reliable molecular markers to early predict or find matastasis.The article will review the research progress of matastasis rel ated genes in gastric cancer.

关 键 词：胃癌 转移相关基因 肿瘤标志物 

分 类 号：R735.2[医药卫生—肿瘤]