悬吊式免气腹腹腔镜手术治疗老年卵巢癌患者的疗效及对预后的影响  

Efficacy of suspended pneumoperitoneum-free laparoscopic surgery in the treatment of elderly patients with ovarian cancer and its impact on prognosis

作　　者：张珂珂 杜玉侠 李云云 ZHANG Keke;DU Yuxia;LI Yunyun(Department of Obstetrics and Gynecology,Xi’an International Medical Center Hospital,Xi’an 710000,Shaanxi,China;Department of Obstetrics and Gynecology,Yan’an Modern Women’s Hospital,Yan’an 716000,Shaanxi,China)

机构地区：[1]西安国际医学中心医院妇产科,西安710000 [2]延安现代妇科医院妇产科,陕西延安7160000

出　　处：《癌症进展》2023年第11期1200-1203,1241,共5页Oncology Progress

摘　　要：目的探讨悬吊式免气腹腹腔镜手术治疗老年卵巢癌患者的疗效及对预后的影响。方法将120例老年卵巢癌患者根据手术方法的不同分为对照组(传统腹腔镜手术)与观察组(悬吊式免气腹腹腔镜手术),每组60例。比较两组患者手术相关指标、应激反应指标、卵巢功能指标、并发症发生情况和预后。结果观察组患者手术时间、术后排气时间、住院时间均明显短于对照组,术中出血量明显少于对照组,差异均有统计学意义(P<0.01)。治疗后,两组患者皮质醇(Cor)、去甲肾上腺素(NE)水平均较治疗前升高,但观察组患者Cor、NE水平均低于对照组,差异均有统计学意义(P<0.05)。治疗后,两组患者促卵泡激素(FSH)、黄体生成素(LH)水平均较治疗前升高,雌二醇(E_2)水平均较治疗前降低,但观察组患者FSH、LH水平均低于对照组,E_2水平高于对照组,差异均有统计学意义(P<0.05)。观察组患者并发症总发生率低于对照组,差异有统计学意义(P<0.05)。观察组患者生存率高于对照组,差异有统计学意义(P<0.05)。结论悬吊式免气腹腹腔镜手术与传统腹腔镜手术在老年卵巢癌患者治疗中均具有显著的效果,且预后良好,但与传统腹腔镜手术相比,悬吊式免气腹腹腔镜手术安全性较高,对患者造成的伤害较小,可有效减轻患者的应激反应,稳定其性激素水平,从而促使患者术后尽早恢复,有助于缩短患者的住院时间。Objective To investigate the efficacy of suspended pneumoperitoneum-free laparoscopic surgery in the treatment of elderly patients with ovarian cancer and its impact on prognosis.Method A total of 120 elderly patients with ovarian cancer were divided into control group(traditional laparoscopic surgery)and observation group(suspended pneumoperitoneum-free laparoscopic surgery)according to different surgical methods,with 60 cases in each group.The surgery-related indicators,stress response indicators,ovarian function indicators,complications,and prognosis were com-pared between the two groups.Result The operation time,postoperative exhaust time,and hospital stay in the observa-tion group were significantly shorter than those in the control group,and the intraoperative blood loss was significantly less than that in the control group,and the differences were statistically significant(P<0.01).After the treatment,the lev-els of cortisol(Cor)and norepinephrine(NE)in the two groups were higher than those before the treatment,while the Cor and NE levels in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the levels of follicle-stimulating hormone(FSH)and luteinizing hormone(LH)in the two groups were higher than those before the treatment,and the levels of estradiol(E2)were lower than those be-fore the treatment,the levels of FSH and LH in the observation group were lower than those in the control group,and the level of E2 was higher than that in the control group,and the differences were statistically significant(P<0.05).The total incidence of complications in the observation group was lower than that in the control group,and the difference was statis-tically significant(P<0.05).The survival rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Suspended pneumoperitoneum-free laparoscopic surgery and traditional laparoscopic surgery both have r

关 键 词：悬吊式免气腹腹腔镜手术 老年 卵巢癌 安全性 预后 

分 类 号：R737.31[医药卫生—肿瘤]