加速康复外科干预对卵巢癌手术患者术后恢复进程、疼痛程度和应激反应的影响  

Effect of enhanced recovery after surgery intervention on the postoperative recovery process,pain level,and stress response of ovarian cancer patients undergoing surgery

作　　者：王平利 刘丽雅[1] 肖静静 WANG Pingli;LIU Liya;XIAO Jingjing(Department of Gynaecology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,He’nan,China)

机构地区：[1]郑州大学第一附属医院妇科,郑州4500000

出　　处：《癌症进展》2023年第11期1249-1252,共4页Oncology Progress

摘　　要：目的探讨加速康复外科(ERAS)干预对卵巢癌手术患者术后恢复进程、疼痛程度和应激反应的影响。方法依据干预方法的不同将96例卵巢癌患者分为常规组和观察组,每组48例,常规组患者给予常规围手术期干预,观察组患者围手术期给予ERAS干预。比较两组患者的手术相关指标、术后恢复进程指标、疼痛程度[视觉模拟评分法(VAS)]、应激反应指标[皮质醇(Cor)、促肾上腺皮质激素(ACTH)、超敏C反应蛋白(hs-CRP)]、术后并发症发生情况。结果两组患者手术时间、术中出血量、淋巴结清扫数目比较,差异均无统计学意义(P﹥0.05)。观察组患者术后进食恢复时间、排气恢复时间、下床活动时间、排便时间、输液治疗时间、住院时间均明显短于常规组,差异均有统计学意义(P﹤0.01)。术后6、12、24、72 h,观察组患者的VAS评分均明显低于常规组,差异均有统计学意义(P﹤0.01)。术后1天,两组患者Cor、ACTH、hs-CRP水平均高于本组术前,观察组患者Cor、ACTH、hs-CRP水平均低于常规组,差异均有统计学意义(P﹤0.05)。观察组患者的术后并发症总发生率为4.17%,低于常规组患者的20.83%,差异有统计学意义(P﹤0.05)。结论ERAS干预能够加快卵巢癌手术患者术后恢复进程,减轻疼痛程度和应激反应,降低术后并发症发生风险。Objective To investigate the effect of enhanced recovery after surgery(ERAS)intervention on the postop-erative recovery process,pain level,and stress response of ovarian cancer patients undergoing surgery.Method A total of 96 ovarian cancer patients were divided into routine group and observation group according to different intervention methods,with 48 cases in each group.Patients in the routine group were given routine perioperative intervention,and pa-tients in the observation group were given ERAS intervention during the perioperative period.The surgery-related indica-tors,postoperative recovery process indicators,pain degree[visual analogue scale(VAS)],stress response indicators[cor-tisol(Cor),adrenocorticotropic hormone(ACTH),high-sensitivity C-reactive protein(hs-CRP)],and postoperative com-plications were compared between the two groups.Result There were no significant differences in operation time,intra-operative blood loss,and number of lymph nodes dissected between the two groups(P>0.05).The postoperative eating re-covery time,exhaust recovery time,ambulation time,defecation time,infusion treatment time,and hospital stay in the ob-servation group were significantly shorter than those in the routine group,and the differences were statistically significant(P<0.01).At 6,12,24,and 72 hours after the operation,the VAS scores of the observation group were significantly lower than those of the routine group,and the differences were statistically significant(P<0.01).One day after the operation,the levels of Cor,ACTH,and hs-CRP in the two groups were higher than those before the operation,and the levels of Cor,ACTH,and hs-CRP in the observation group were lower than those in the routine group,and the differences were statisti-cally significant(P<0.05).The total incidence of postoperative complications in the observation group was 4.17%,which was lower than 20.83%in the routine group,and the difference was statistically significant(P<0.05).Conclusion The ERAS intervention could speed up the postoperative recover

关 键 词：卵巢癌 加速康复外科 术后恢复 应激反应 

分 类 号：R737.31[医药卫生—肿瘤]