改良半离体自体小肠移植治疗肠系膜根部受侵胆管癌1例报道  

Modified semi-ex vivo small intestinal autotransplantation for cholangiocarcinoma with mesenteric root invasion:a case report

作　　者：游欣雨 庞北川 左邦佑 蒋佶朋 程东辉 杨冲 郝建杰 刘涛 张宇 YOU Xinyu;PANG Beichuan;ZUO Bangyou;JIANG Jipeng;CHENG Donghui;YANG Chong;HAO Jianjie;LIU Tao;ZHANG Yu(Affiliated Hospital of University of Electronic Science and Technology of China·Department of Hepatobiliary and Pancreatic Surgery,Sichuan Provincial People’s Hospital,Chengdu 610072,P.R.China)

机构地区：[1]电子科技大学附属医院·四川省人民医院肝胆胰外科,成都610072

出　　处：《中国普外基础与临床杂志》2023年第7期777-781,共5页Chinese Journal of Bases and Clinics In General Surgery

基　　金：四川省科学技术厅科技计划项目(项目编号:2021YFS0375)。

摘　　要：目的探索胆管癌远端侵犯肠系膜根部患者行改良半离体自体小肠移植的可行性与安全性。方法回顾性分析四川省人民医院2022年10月收治的1例胆管癌术后复发性肠系膜根部受侵患者的临床病理资料。结果本例患者为一40岁男性,术前影像学检查示肿瘤包绕肠系膜上动脉及空肠动脉分支。患者术前一般情况良好,心、肺、肝、肾功能正常,经评估患者能耐受手术,实施改良半离体自体小肠移植,术后恢复良好,术后第14天出院。术后病理诊断为胆管腺癌。截至2023年4月,患者已在门诊随访5个月,随访期间患者一般情况良好,未见复发或转移证据。结论从对本病例回顾性分析结果看,对于肿瘤侵犯肠系膜根部的胆管癌患者采用改良半离体自体小肠移植治疗可以安全成功实现,为此类患者提供了一种可以获得生存机会的治疗选择。Objective To explore the feasibility and safety of modified semi-ex vivo small intestinal autotransplantation(IAT)in patients with distal cholangiocarcinoma(CC)involving mesenteric root.Method The clinicopathologic data of the patient with relapse after CC surgery admitted to Sichuan Provincial People’s Hospital on October 2022 were retrospectively analyzed.Results The patient was a 40 years old male.The preoperative imaging showed that the superior mesenteric artery(SMA)and jejunal artery was surrounded by the tumor.The preoperative condition was good and the heart,lung,liver,and kidney functions were normal.The patient could tolerate surgery,then the modified semi-ex vivo IAT was performed.The patient recovered well after surgery and discharged on the 14th postoperative day.The postoperative pathological diagnosis result showed that it was CC.The patient was well and without recurrence or metastasis during following-up in the outpatient service for 5 months until April 2023.Conclusions From the retrospective analysis of this case,it can be realized that the modified semi-ex vivo IAT for patients with tumor involving the mesenteric root,it is safe and feasible.A treatment option can be provided for such patient.

关 键 词：远端胆管癌 自体小肠移植 肠系膜上动脉 

分 类 号：R735.8[医药卫生—肿瘤]