Systematic review of fibroblastic rheumatism:A case report  

作　　者：Hua Guo Qian Liang Chen Dong Qing Zhang Zhi-Feng Gu 

机构地区：[1]Department of Rheumatology,Affiliated Hospital of Nantong University,Nantong 226001,Jiangsu Province,China [2]Department of Pathology,Affiliated Hospital of Nantong University,Nantong 226001,Jiangsu Province,China

出　　处：《World Journal of Clinical Cases》2023年第21期5136-5146,共11页世界临床病例杂志

摘　　要：BACKGROUND Fibroblastic rheumatism(FR)is a rare fibroproliferative disease with an unknown etiology.The absence of typical symptoms makes early diagnosis challenging.This study aims to systematically review FR cases and present a case from our center to provide a comprehensive description of the clinical manifestations,diagnosis,and treatment,thereby assisting clinicians in early identification and timely management of FR,ultimately leading to improved prognosis.CASE SUMMARY FR is a rare fibroproliferative disease with an unknown etiology.It is characterized by rapidly progressive and destructive symmetrical inflammatory multiple arthritis.Here,we present a rare case of a 50-year-old female with symmetric inflammatory polyarthritis.We highlight the importance of a comprehensive medical history,histopathology,immunohistochemistry,and clinical manifestations of skin nodules,arthralgia,and arthritis for successful disease diagnosis.Despite employing non-steroidal anti-inflammatory drugs,corticosteroids,methotrexate,and tacrolimus,the patient's symptoms did not resolve,and joint destruction continued to progress.Early diagnosis,aggressive treatment with appropriate use of steroids and immunosuppressants,and further research to identify effective treatment strategies are crucial in preventing detrimental joint destruction and limb contractures.CONCLUSION A comprehensive review of the available literature emphasizes the importance of early and accurate diagnosis coupled with appropriate treatment for achieving favorable outcomes and preventing joint destruction and limb contractures.

关 键 词：Fibroblastic rheumatism Systematic review DIAGNOSTIC Case report 

分 类 号：R593.21[医药卫生—内科学]