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作 者:Hong-Zhen Yu Almaz Borjigidai Ming-Hai Fu
机构地区:[1]Key Laboratory of Tropical Translational Medicine of Ministry of Education,Hainan Provincial Key Laboratory for Research and Development of Tropical Herbs,School of Pharmacy,Hainan Medical University,Haikou 571199,China [2]Key Laboratory of Ethnomedicine of Ministry of Education,Center on Translational Neuroscience,School of Pharmacy,Minzu University of China,Beijing 100081,China
出 处:《TMR Integrative Medicine》2023年第16期1-14,共14页TMR整合医学
基 金:This research was funded by the National Natural Science Foundation of China(82260773);National Key R&D Program:Intergovernmental Cooperation in International Science and Technology Innovation(2022YFE0119300);Central Government Guided Local Scientific and Technological Development Project(2021ZY0015);Science and Technology Young Talents Development Project of Inner Mongolia Autonomous Region(NJYT22048).
摘 要:Corydalis bungeana Turcz.(CB)is a medicinal herb with significant medicinal value in traditional Chinese medicine.This paper reviews the progress of research on CB’s botany,quality control,phytochemistry,pharmacology and toxicity.The plant’s information was gathered from scientific databases such as PubMed,GeenMedical,Springer Link(https://link.springer.com),Chinese National Knowledge Infrastructure,Pharmacopoeia and Flora.Currently,137 phytochemicals have been identified and isolated from CB,including alkaloids,flavonoids,amino acids,terpenoids,coumarins and organic acids.In addition,many phytochemicals reported various antiinflammatory,antibacterial,antiviral,antitumor,analgesic,hepatoprotective,immunomodulatory,neuromodulatory,and lipid reduction activities.However,the study of its toxicity is still at the preliminary exploration stage and needs further intensive exploration.Herein,we provide an in-depth investigation of the progress of CB to elucidate the underlying mechanisms of activity of CB extracts and its major components,deliver valuable resources and information for further research and rational drug use,and explore the potential research directions and prospects of CB.
关 键 词:Corydalis bungeana Turcz. BOTANY quality control PHYTOCHEMISTRY PHARMACOLOGY TOXICITY
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