Reoperation for heterochronic intraductal papillary mucinous neoplasm of the pancreas after bile duct neoplasm resection:A case report  

作　　者：Gang Xiao Tao Xia Yi-Ping Mou Yu-Cheng Zhou 

机构地区：[1]Department of Hepatopancreatobiliary Surgery,Shaoxing People’s Hospital,Shaoxing 312000,Zhejiang Province,China [2]Division of Gastrointestinal and Pancreatic Surgery,Department of General Surgery,Zhejiang Provincial People’s Hospital(People’s Hospital of Hangzhou Medical College),Key Laboratory of Gastroenterology of Zhejiang Province,Hangzhou 310014,Zhejiang Province,China

出　　处：《World Journal of Gastrointestinal Surgery》2023年第7期1542-1548,共7页世界胃肠外科杂志（英文版）（电子版）

摘　　要：BACKGROUND Intraductal papillary neoplasm of the bile duct(IPNB)and intraductal papillary mucinous neoplasm(IPMN)of the pancreas have similar pathological manifestations.However,they often develop separately and it is rare for both to occur together.Patients presenting with heterochronic IPMN after IPNB are prone to be misdiagnosed with tumor recurrence.CASE SUMMARY A 67-year-old male patient was admitted 8.5 years after IPNB carcinoma and 4 years after the discovery of a pancreatic tumor.A left hepatic bile duct tumor with distal bile duct dilatation was found 8.5 years ago by the computed tomography;therefore,a left hepatectomy was performed.The postoperative pathological diagnosis was malignant IPNB with negative cutting edge and pathological stage T1N0M0.Magnetic resonance imaging 4 years ago showed cystic lesions in the pancreatic head with pancreatic duct dilatation,and carcinoembryonic antigen continued to increase.Positron emission tomography showed a maximum standard uptake value of 11.8 in the soft tissue mass in the pancreatic head,and a malignant tumor was considered.Radical pancreatoduodenectomy was performed.Postoperative pathological diagnosis was pancreatic head IPMN with negative cutting edge,pancreaticobiliary type,stage T3N0M0.He was discharged 15 d after the operation.Follow-up for 6 mo showed no tumor recurrence,and quality of life was good.CONCLUSION IPNB and IPMN are precancerous lesions with similar pathological characteristics and require active surgery and long-term follow-up.

关 键 词：Intraductal papillary neoplasm of the bile duct Intraductal papillary mucinous neoplasm of the pancreas PANCREATODUODENECTOMY Heterochronous tumor REOPERATION Case report 

分 类 号：R735.9[医药卫生—肿瘤]