钆喷酸葡胺多期增强MRI预测原发性肝癌腹膜后淋巴结转移的临床研究  

Clinical Study of Gadopentetate Dimeglumine-Enhanced MRI for the Prediction of Retroperitoneal Lymph Node Metastasis in Primary Liver Cancer

作　　者：吕宛平 乔亚丽 LV Wanping;QIAO Yali(Nanyang First People's Hospital,Nanyang,473000)

机构地区：[1]河南省南阳市第一人民医院,473000

出　　处：《实用癌症杂志》2023年第8期1329-1332,共4页The Practical Journal of Cancer

摘　　要：目的 探究钆喷酸葡胺多期增强磁共振成像(magnetic resonance imaging,MRI)预测原发性肝癌(primary liver cancer,PLC)腹膜后淋巴结转移的临床效果。方法 选取70例PLC患者,常规MRI检查后开启多期增强MRI检查,患者接受钆喷酸葡胺多期增强MRI扫描,2 ml/kg,经外周肘静脉团注,速率是2.0~2.5 ml/s,注射后使用20 ml生理盐水冲洗导管。以病理学检查结果为标准,比较两种成像模式下PLC、PLC腹膜后淋巴结转移诊断准确率,以及两种成像模式诊断PLC腹膜后淋巴结转移的灵敏度和特异度。结果 常规MRI扫描诊断PLC、PLC腹膜后淋巴结转移的准确率为82.86%,经钆喷酸葡胺多期增强MRI扫描准确率为95.71%,钆喷酸葡胺多期增强MRI扫描的诊断准确率高于常规MRI扫描(P<0.05);使用钆喷酸葡胺多期增强MRI诊断PLC腹膜后淋巴结转移的灵敏度和特异度高于常规MRI(P<0.05)。结论 钆喷酸葡胺多期增强MRI可提升诊断原发性肝癌腹膜后淋巴结转移准确率,建议临床使用。Objective To explore the clinical effect of gadopentetate dimeglumine-enhanced Magnetic Resonance Imaging(MRI) for the prediction of retroperitoneal lymph node metastasis in primary liver cancer(PLC).Methods 70 patients with PLC were enrolled.All patients received contrast-enhanced MRI after conventional MRI scan.The patients were given gadopentetate dimeglumine at a dose of 2ml/kg and a rate of 2.0~2.5 ml/s via the peripheral antecubital vein.The remaining in the tubing was flushed out with 20 ml of normal saline.Based on the pathological examination results,the diagnostic accuracy of 2 imaging modes in the diagnosis of PLC and PLC retroperitoneal lymph node metastasis,and the sensitivity and specificity of the 2 imaging modes in the diagnosis of PLC retroperitoneal lymph node metastasis were compared.Results In the diagnosis of PLC and PLC retroperitoneal lymph node metastasis,the accuracy of conventional MRI scan was 82.86%,which was notably lower than 95.71% of gadopentetate dimeglumine-enhanced MRI scan,with statistical difference(P<0.05).The sensitivity and specificity of gadopentetate dimeglumine-enhanced MRI scan in the diagnosis of retroperitoneal lymph node metastasis in PLC were higher than those of conventional MRI scan(P<0.05).Conclusion Gadopentetate dimeglumine-enhanced MRI can improve the diagnostic accuracy of retroperitoneal lymph node metastasis of primary liver cancer,which is worthy of promotion.

关 键 词：钆喷酸葡胺 多期增强 MRI 原发性肝癌 腹膜后淋巴结转移 准确率 

分 类 号：R735.7[医药卫生—肿瘤]