宫颈癌术后盆腔复发患者放疗的临床效果及预后相关因素分析  

Clinical Efficacy and Prognostic Factors of Radiotherapy in Patients with Pelvic Recurrence After Cervical Cancer Surgery

作　　者：严倩 金洋 王晶 黄艳萍 YAN Qian;JIN Yang;WANG Jing(Zhengzhou University Affiliated Cancer Hospital(Henan Cancer Hospital),Zhengzhou,450000)

机构地区：[1]郑州大学附属肿瘤医院,河南省肿瘤医院,450000

出　　处：《实用癌症杂志》2023年第8期1365-1367,共3页The Practical Journal of Cancer

摘　　要：目的 探讨宫颈癌术后盆腔复发患者放疗的临床效果及预后相关因素。方法 选择宫颈癌术后盆腔复发患者145例作为研究对象,依据宫颈癌术后盆腔复发患者放疗效果将患者分为完全缓解组(88例)及未完全缓解组(57例)。分析治疗效果、宫颈癌术后盆腔复发患者放疗效果的影响因素。对患者进行3年随访,分析预后。结果145例患者经放疗后完全缓解(CR)88例,部分缓解(PR)36例,疾病进展(PD)21例,治疗有效率为85.52%。未完全缓解组Ⅱa~Ⅱb期病理分期、盆壁受侵发生率均高于完全缓解组,差异有统计学意义(P<0.05);病理分期、盆壁受侵是影响宫颈癌术后盆腔复发患者放疗治疗效果的独立危险因素(P<0.05);术前不同病理分期3年生存率比较,差异有统计学意义(P<0.05)。结论 在临床治疗中需注意患者肿瘤病理分期、影像学检查盆壁是否受侵,制定个性化的放疗方案,以延长患者无瘤生存时间及提高生存质量。Objective To explore the clinical efficacy and prognostic factors of radiotherapy for patients with pelvic recurrence after cervical cancer surgery.Methods 145 patients with pelvic recurrence after cervical cancer surgery were selected as the research subjects.Based on the radiotherapy effect of patients with pelvic recurrence after cervical cancer surgery,the patients were divided into a complete remission group(88 cases) and an incomplete remission group(57 cases).Analyze the single and multiple factors of treatment effect and radiotherapy effect for patients with pelvic recurrence after cervical cancer surgery,and conduct a 3-year follow-up to analyze the prognosis.Results Among 145 patients,88 had complete remission(CR),36 had partial remission(PR),and 21 had disease progression(PD) after radiotherapy.The effective rate of treatment was 85.52%;The pathological staging and incidence of pelvic wall invasion in the incomplete remission group were higher than those in the complete remission group,with statistical significance;Pathological staging and pelvic wall invasion are independent risk factors that affect the effectiveness of radiotherapy in patients with postoperative pelvic recurrence of cervical cancer;There was a statistically significant difference in 3-year survival rate among different pathological stages before surgery.Conclusion In clinical treatment,it is necessary to pay attention to the pathological staging of the patient's tumor,imaging examination of the pelvic wall for invasion,and develop personalized radiotherapy plans to prolong the patient's tumor free survival time and improve their quality of life.

关 键 词：宫颈癌 盆腔复发 放疗治疗 预后效果 因素分析 

分 类 号：R737.33[医药卫生—肿瘤]