观察不同镇痛方式对直结肠癌根治术后患者血流动力学以及睡眠质量的影响  

To Observe the Effects of Different Analgesic Methods on Hemodynamics and Sleep Quality in Patients with Colorectal Cancer after Radical Surgery

作　　者：李宜聪 董晓禹 LI Yicong;DONG Xiaoyu(Songyuan Jilin Oilfield Hospital,Songyuan 138000,China)

机构地区：[1]吉林省松原市松原吉林油田医院,松原138000

出　　处：《世界睡眠医学杂志》2023年第5期975-977,共3页World Journal of Sleep Medicine

摘　　要：目的:观察不同镇痛方式对直结肠癌根治术后患者血流动力学以及睡眠质量的影响。方法:选取2021年12月至2022年3月吉林省松原市松原吉林油田医院实施直结肠癌根治手术治疗的患者90例作为研究对象,按照随机数字表法分为观察组和对照组,每组45例。对照组给予静脉镇痛,观察者给予硬膜外镇痛麻醉。采用视觉模拟评分法(VAS)比较2组患者干预前后的疼痛感受,比较2组患者心率、舒张压以及收缩压变化,采用匹兹堡睡眠质量指数(PSQI)比较2组患者的睡眠质量变化情况,并比较2组患者严重睡眠障碍的发生率。结果:干预后,观察组患者不同时刻的VAS评分均显著低于对照组,观察组切皮时心率、收缩压、舒张压均显著低于对照组,差异均有统计学意义(均P<0.05);与术前比较,术后30 d,观察组患者的PSQI评分及严重睡眠障碍发生率均显著低于对照组,差异均有统计学意义(均P<0.05)。结论:对于直结肠癌手术治疗患者,采用硬膜外麻醉使患者切片时的血流动力学参数更加稳定,术后疼痛缓解更明显,能够显著改善睡眠效果,值得在临床上推广使用。Objective:To observe the effects of different analgesia on hemodynamics and sleep quality in patients with colorectal cancer after radical surgery.Methods:A total of 90 patients who underwent radical surgery for colorectal cancer in Songyuan Jilin Oilfield Hospital from December 2021 to March 2022 were selected as the research objects,and were divided into observation group and control group according to the random number table method,with 45 cases in each group.The control group was given intravenous analgesia,and the observer was given epidural analgesia.Visual Analogue Scale(VAS)was used to compare the pain perception before and after the intervention,the changes in heart rate,diastolic blood pressure and systolic blood pressure of the 2 groups were compared as well,the changes of sleep quality of the two groups were compared by Pittsburgh Sleep Quality Index(PSQI),and the incidence of severe sleep disorders were compared between the 2 groups.Results:After intervention,VAS scores of the observation group were significantly lower than the control group at different times,the heart rate,systolic blood pressure and diastolic blood pressure of observers were significantly lower than the control group,and the differences between the 2 groups were statistically significant(P s<0.05).The PSQI scores and the incidence of severe sleep disorders in observation group 30 days after surgery were significantly lower than those of the control group compared with before operation,and the differences between 2 groups were statistically significant(P s<0.05).Conclusion:For patients undergoing surgical treatment for colorectal cancer,the hemodynamic parameters of patients undergoing section with epidural anesthesia are more stable,and the postoperative pain relief is more obvious,which can significantly improve sleep effect,and is worthy of clinical promotion.

关 键 词：硬膜外镇痛麻醉 结肠癌根治术 血流动力学 睡眠质量 睡眠障碍 

分 类 号：R735.37[医药卫生—肿瘤] R735.35[医药卫生—临床医学] R338.63