PSS-4快速评估功能性消化不良患者压力影响的研究  

Study on Effect of PSS⁃4 on Rapid Assessment of Stress in Patients With Functional Dyspepsia

作　　者：王萍[1] 杜丽梅 王茜 明文[1] 陈镜晶 贺国斌[1] WANG Ping;DU Limei;WANG Xi;MING Wen;CHEN Jingjing;HE Guobin(Department of Gastroenterology,Affiliated Hospital of North Sichuan Medical College,Nanchong,Sichuan Province,637000;Department of Gastroenterology,Rongchang People’s Hospital,Chongqing)

机构地区：[1]川北医学院附属医院消化内科,637000 [2]重庆市荣昌区人民医院消化内科

出　　处：《胃肠病学》2022年第7期404-409,共6页Chinese Journal of Gastroenterology

摘　　要：背景:功能性消化不良(FD)患者伴有不同程度的心理压力,临床医师对患者心理压力的量化评估不足。目的:探讨4项条目的知觉压力量表(PSS-4)与10项条目的知觉压力量表(PSS-10)评估的心理压力对FD患者的消化不良症状、焦虑、抑郁、躯体化和生命质量的影响。方法:采集2021年3月—2022年3月于川北医学院附属医院就诊的符合罗马Ⅳ标准的357例FD患者,并行PSS-4、PSS-10、7项广泛性焦虑障碍量表(GAD-7)、9项患者健康问卷(PHQ-9)、躯体化症状群量表(改编的PHQ-15)、消化不良症状严重程度量表(DSS)、Nepean消化不良指数简表(NDI)评分。分析PSS-4、PSS-10对FD患者的消化不良症状、焦虑、抑郁、躯体化和生命质量的影响。结果:相关性分析结果显示PSS-4(r=0.152,P=0.004)、PSS-10(r=0.194,P=0.000)与DSS相关;PSS-4(r=0.341,P=0.000)、PSS-10(r=0.389,P=0.000)与改编的PHQ-15相关;PSS-4(r=0.239,P=0.000)、PSS-10(r=0.327,P=0.000)与NDI相关;PSS-4与焦虑(r=0.561,P=0.000)、抑郁(r=0.449,P=0.000)相关;PSS-10与焦虑(r=0.680,P=0.000)、抑郁(r=0.524,P=0.000)相关。多元线性回归结果显示,PSS-4评估的心理压力(β=0.180,P=0.000)、DSS(β=0.390,P=0.000)、FD分型(β=-0.116,P=0.024)是FD患者NDI的影响因素。PSS-10评估的心理压力(β=0.268,P=0.000)、DSS(β=0.360,P=0.000)、FD分型(β=-0.116,P=0.021)是FD患者NDI的影响因素。结论:PSS-4、PSS-10评估的心理压力对FD患者焦虑、抑郁、躯体化、DSS和NDI均有影响,但PSS-4更简短,临床上可用PSS-4快速初步评估心理压力对FD患者的影响。Patients with functional dyspepsia(FD)are accompanied by different degree of psychological stress,and clinicians usually have insufficient quantitative assessment of patients’psychological stress.Aims:To explore the effect of psychological stress assessed by 4‑item perceived stress scale(PSS‑4)and 10‑item perceived stress scale(PSS‑10)on dyspepsia symptoms,anxiety,depression,somatization and quality of life in FD patients.Methods:A total of 357 FD patients met RomeⅣcriteria from March 2021 to March 2022 at Affiliated Hospital of North Sichuan Medical College were recruited.Score of PSS‑4,PSS‑10,generalized anxiety disorder‑7(GAD‑7),patient healthy questionnaire‑9(PHQ‑9),adapted patient healthy questionnaire‑15(adapted PHQ‑15),dyspepsia symptom severity(DSS),Nepean dyspepsia indexshort form(NDI)were performed.Effects of PSS‑4,PSS‑10 on dyspepsia symptoms,anxiety,depression,somatization and quality of life in FD patients were analyzed.Results:Correlation analysis showed that PSS‑4(r=0.152,P=0.004)and PSS‑10(r=0.194,P=0.000)were correlated with DSS;PSS‑4(r=0.341,P=0.000)and PSS‑10(r=0.389,P=0.000)were correlated with adapted PHQ‑15;PSS‑4(r=0.239,P=0.000)and PSS‑10(r=0.327,P=0.000)were correlated with NDI;PSS‑4(r=0.561,P=0.000)and PSS‑10(r=0.680,P=0.000)were correlated with anxiety;PSS‑4(r=0.449,P=0.000)and PSS‑10(r=0.524,P=0.000)were correlated with depression.Multiple linear regression analysis showed that psychological stress assessed by PSS‑4(β=0.180,P=0.000),DSS(β=0.390,P=0.000)and FD classification(β=-0.116,P=0.024)were the influencing factors of NDI,and the psychological stress assessed by PSS‑10(β=0.268,P=0.000),DSS(β=0.360,P=0.000)and FD classification(β=-0.116,P=0.021)were the influencing factors of NDI.Conclusions:Psychological stress assessed by PSS‑4,PSS‑10 have effects on anxiety,depression,somatization,DSS and NDI in FD patients,and PSS‑4 is shorter.These results suggest that PSS‑4 can be used clinically to assess quickly and initi

关 键 词：功能性消化不良 知觉压力量表 心理压力 焦虑 抑郁 生命质量 

分 类 号：R57[医药卫生—消化系统]