中国老年人感觉障碍与死亡风险关联的研究  

Association between sensory impairment and mortality among older Chinese

作　　者：傅言一 郑卫军[1] FU Yan-yi;ZHENG Wei-jun(School of Public Health,Zhejiang Chinese Medical University,Hangzhou,Zhejiang 310000,China)

机构地区：[1]浙江中医药大学公共卫生学院,浙江杭州310000

出　　处：《现代预防医学》2023年第14期2669-2675,共7页Modern Preventive Medicine

摘　　要：目的探讨中国65岁以上老年人群感觉障碍程度与死亡的关系。方法本研究使用了来自中国老年健康影响因素跟踪调查(CLHLS)2011—2018数据和中国健康与养老追踪调查(CHARLS)2011—2018数据,分别纳入8268例和2921例样本,将老年人的感觉障碍水平划分为4个类别,比较不同感觉障碍组的粗死亡率,采用多因素Cox回归模型调整混杂因素,通过固定效应模型汇总危险比,探讨不同感觉障碍人群的死亡风险差别。结果在CLHLS队和CHARLS队列中,分别随访39835人年(平均每人4.8年)和18785人年(平均每人6.4年),发生了3713例死亡事件(44.9%)和752例死亡事件。经多因素Cox比例风险回归分析结果显示,调整年龄、性别、居住情况、受教育程度、婚姻、吸烟、饮酒、心脏病及高血压等协变量后,通过固定效应模型汇总危险比后,与无感觉障碍人群相比,仅听力障碍、仅视力障碍和双重感觉障碍的老年人的死亡风险分别增加了37%(HR=1.37,95%CI:1.23~1.51)、44%(HR=1.44,95%CI:1.20~1.73)、45%(HR=1.45,95%CI:1.30~1.63)。结论基于CLHLS和CHARLS数据分析发现我国老年人感觉障碍与死亡风险存在统计学关联。Objective To explore the relationship between sensory impairment and mortality in elderly people over 65 years old in China.Methods Based on data from CLHLS 2011-2018 and CHARLS 2011-2018,8268 and 2921 older adults were included respectively,and the sensory impairment could be categorized into four groups.The crude mortality rates of different groups were compared.The multivariate COX regression model was used to adjust the mixed factors to explore the differences in the mortality of different levels of sensory impairment.The hazard ratios(HRs)of different models were analyzed separately in CLHLS and CHARLS cohorts and then pooled the cohort-specific HRs to obtain a summarized risk estimate using fixed effect models.Results A total of 39835 person-years(average 4.8 years per person)and 18785 person-years(average 6.4 years per person)were observed in two cohorts.3713 deaths(44.9%)and 752 deaths(25.7%)occurred in CLHLS and CHARLS cohort study.After adjusting the covariates of demographic characteristics,smoking,drinking,heart disease and hypertension by Cox regression control and pooling the cohort-specific HRs to obtain a summarized risk estimate using fixed effect models,it was found that the risk of death increased by 37%(HR=1.37,95%CI:1.23-1.51),44%(HR=1.44,95%CI:1.20-1.73)and 45%(HR=1.45,95%CI:1.30-1.63)in older people with hearing impairment only,visual impairment only and dual sensory impairment respectively compared to those without sensory impairments.Conclusion Our results demonstrates that there is a statistical association between sensory impairment and mortality risk in older adults based on the data from CLHLS and CHARLS.

关 键 词：老年人 死亡 感觉障碍 CLHLS数据库 CHARLS数据库 

分 类 号：R749.16[医药卫生—神经病学与精神病学]