喉前淋巴结转移对甲状腺乳头状癌诊疗价值的研究进展  

Research progress in the diagnostic and therapeutic value of Delphian lymph node metastasis in papillary thyroid carcinoma

作　　者：樊逸隽 杨枫 王玮[1,3] 殷鹤英[2] 刘俊 Fan Yijun;Yang Feng;Wang Wei;Yin Heying;Liu Jun(Clinical Medical College of Shanghai First Affiliated Hospital of Nanjing Medical University,Shanghai 201620,China;Shanghai Songjiang District Central Hospital,Shanghai 201600,China;Department of Mammary and Thyroid Surgery,the First People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 201620,China)

机构地区：[1]南京医科大学附属上海一院临床医学院,201620 [2]上海松江区中心医院,201600 [3]上海交通大学医学院附属第一人民医院乳腺甲状腺外科,201620

出　　处：《中华普通外科学文献（电子版）》2023年第4期306-310,共5页Chinese Archives of General Surgery(Electronic Edition)

摘　　要：喉前淋巴结(DLN)对于甲状腺乳头状癌(PTC)的意义一直存在争议。有研究者认为其是PTC的前哨淋巴结,但也有认为其对于PTC进展和预后的判断完全不可靠。众多研究认为PTC肿瘤直径>1 cm、腺外侵犯、淋巴管侵犯、肿瘤位于腺叶上1/3和(或)峡部是DLN转移的重要风险因素,同时DLN转移在预测其他中央区淋巴结转移(CLNM)、对侧CLNM、颈侧区淋巴结转移、对侧腺叶隐匿性癌方面具有非常重要的意义,能提供更多关于手术及淋巴结清扫范围的建议。本文针对PTC中DLN转移风险因素作一综述。The significance of Delphian lymph node(DLN)for papillary thyroid carcinoma(PTC)has been controversial.Some investigators considered DLN as a sentinel lymph node in PTC,but others believed that it is completely unreliable in judging the progress and prognosis of PTC.In this article,we summarized the risk factors of DLN metastasis(DLNM)in PTC in detail.Numerous research studies have identified PTC tumor diameter greater than 1 cm,extrathyroidal extension,lymphovascular invasion,and tumor location in the upper third of the glandular lobe and/or isthmus as important risk factors for DLNM.At the same time,DLNM is of great significance in predicting other central lymph node metastasis(CLNM),contralateral CLNM,lateral cervical lymph node metastasis,and occult thyroid carcinoma in the contralateral glandular lobe.This can give more advice on the extent of surgery and lymph node dissection.

关 键 词：喉前淋巴结 淋巴结转移 甲状腺乳头状癌 风险因素 研究进展 

分 类 号：R736.1[医药卫生—肿瘤]