DISCO成像技术在前列腺增生与前列腺癌鉴别诊断中的应用价值  

Application value of DISCO imaging in differential diagnosis of benign prostatic hyperplasia and prostate cancer

作　　者：李全喜[1] 唐辉军 唐友杰 杨飞[2] Quanxi Li;Huijun Tang;Youjie Tang;Fei Yang(Department of Radiology,the Third Affiliated Hospital of Sun Yat-sen University Lingnan Hospital,Guangzhou 510630,China;Department of Urology,the Third Affiliated Hospital of Sun Yat-sen University Lingnan Hospital,Guangzhou 510630,China)

机构地区：[1]中山大学附属第三医院岭南医院放射科,广州510530 [2]中山大学附属第三医院岭南医院泌尿外科,广州510530

出　　处：《中华腔镜泌尿外科杂志（电子版）》2023年第4期332-335,共4页Chinese Journal of Endourology(Electronic Edition)

基　　金：广东省医学科学技术研究基金项目(A2019560)。

摘　　要：目的探讨笛卡尔采集的K空间共享三维容积快速动态成像(DISCO)技术在前列腺增生(BPH)与前列腺癌(PCa)鉴别诊断中的应用价值。方法收集2020年1月至2021年12月在中山大学附属第三医院岭南医院诊治的100例前列腺疾病患者的临床资料,全部患者均行MRI检查,后经手术病理结果确定诊断,其中PCa患者40例,BPH患者60例,使用MRI联合DISCO成像技术测定血流动力学参数:前向容积转移常数(K^(trans))、每单位体积组织的血管外细胞外间隙容积(Ve)、初始增强曲线下面积(IAUGC)、最大增强斜率(MaxSlope)、对比增强比率(CER),并运用ROC曲线评价各个参数的诊断价值。结果与BPH组相比,PCa组病变的K^(trans)、CER、IAUGC、MaxSlope、Ve均升高,差异具有统计学意义(P<0.05),K^(trans)、CER、IAUGC、MaxSlope、Ve诊断PCa的ROC曲线下面积分别为0.646、0.697、0.713、0.613、0.669。结论DISCO成像技术间接地反映BPH与PCa之间的病理差异性,能对BPH与PCa鉴别诊断提供重要的参考价值。Objective To explore the application value of differential subsampling with cartesian ordering(DISCO)imaging technique in the differential diagnosis of prostate cancer(PCa)and benign prostatic hyperplasia(BPH).Methods The clinical data of 100 patients with prostatic diseases treated in Lingnan Hospital of the Third Affiliated Hospital of Sun Yat-sen University from January 2020 to December 2021 were collected.All patients underwent MRI examination,which was confirmed by biopsy pathology or surgical pathology,including 40 patients with PCa and 60 patients with BPH,MRI combined with DISCO imaging technology was used to measure the hemodynamic parameters,such as K^(trans),Ve,IAUGC,MaxSlope and CER.The diagnostic value of each parameter was evaluated by ROC curve.Results Compared with BPH group,K^(trans),CER,IAUGC,MaxSlope and Ve in PCa group were significantly higher(P<0.05).The areas under the ROC curve of K^(trans),CER,IAUGC,Ve and MaxSlope in the diagnosis of PCa were 0.646,0.697,0.713,0.613 and 0.669,respectively.Conclusion DISCO imaging technology can provide important reference value for the differential diagnosis of BPH and PCa.

关 键 词：DISCO成像技术 前列腺增生 前列腺癌 鉴别诊断 

分 类 号：R737.25[医药卫生—肿瘤]