EUS-FNA联合MOSE对提高组织穿刺活检诊断率的评价研究  

Study on application value of EUS-FNA combined with MOSE in improving the diagnostic rate of tissue biopsy

作　　者：罗程[1] 徐永成[1] 陈惠新[1] LUO Cheng;XU Yong-cheng;CHEN Hui-xin(Huizhou Central People's Hospital,Huizhou 516001,China)

机构地区：[1]惠州市中心人民医院,516001

出　　处：《中国实用医药》2023年第15期99-102,共4页China Practical Medicine

基　　金：惠州市科技计划项目(项目编号:2021WC0106418)项目名称:EUS-FNA联合MOSE对提高组织穿刺活检诊断率的评价研究。

摘　　要：目的探讨超声内镜引导下细针穿刺活组织检查(EUS-FNA)联合肉眼现场评估(MOSE)在消化道及周围占位性疾病中的应用价值。方法50例消化道及周围占位性疾病患者,应用随机数字表法分为观察组和对照组,每组25例。观察组行EUS-FNA联合MOSE,对照组穿刺获取组织不予任何处理。对比两组穿刺次数、穿刺时间、住院时间、一次性穿刺成功率、取材阳性率、阳性预测值及并发症发生率。结果观察组一次性穿刺成功率为72.00%(18/25),高于对照组的40.00%(10/25),差异具有统计学意义(P<0.05)。观察组取材阳性率92.00%(23/25)、阳性预测值80.00%(20/25)高于对照组的60.00%(15/25)、40.00%(10/25),差异有统计学意义(P<0.05);两组并发症发生率比较差异无统计学意义(P>0.05)。观察组穿刺次数(3.65±0.32)次少于对照组的(4.89±0.45)次,穿刺时间(25.98±1.01)min、住院时间(5.26±0.52)d短于对照组的(35.52±2.36)min、(7.45±1.05)d,差异有统计学意义(P<0.05)。结论EUS-FNA获取组织的同时联合MOSE能有效提高消化道及周围占位性疾病病理组织活检阳性率,从而有助于临床判断疾病性质及制定治疗方案。Objective To discuss the application value of endoscopic ultrasonography-guided fine needle aspiration(EUS-FNA)combined with macroscopic on-site quality evaluation(MOSE)in space-occupying lesions of gastrointestinal adjacent tissue.Methods A total of 50 patients with space-occupying lesions of gastrointestinal adjacent tissue were divided into observation group and control group according to the random numerical table,with 25 cases in each group.In the observation group,EUS-FNA combined with MOSE was performed,while in the control group,tissue was obtained by puncture without any treatment.The number of punctures,puncture time,hospitalization time,success rate of one-time puncture,positive sampling rate,positive predictive value,and incidence of complications were compared between the two groups.Results The success rate of one-time puncture was 72.00%(18/25)in the observation group,which was higher than that of 40.00%(10/25)in the control group,and the difference was statistically significant(P<0.05).The positive sampling rate of 92.00%(23/25)and positive predictive value of 80.00%(20/25)in the observation group were higher than those of 60.00%(15/25)and 40.00%(10/25)in the control group,and the differences were statistically significant(P<0.05).There was no statistically significant difference in incidence of complications between the two groups(P>0.05).The number of punctures of(3.65±0.32)times in the observation group were less than that of(4.89±0.45)times in the control group;the puncture time of(25.98±1.01)min and hospitalization time of(5.26±0.52)d in the observation group were shorter than those of(35.52±2.36)min and(7.45±1.05)d in the control group;the differences were statistically significant(P<0.05).Conclusion EUS-FNA tissue acquisition combined with MOSE can effectively improve the positive biopsy rate of space-occupying lesions of gastrointestinal adjacent tissue,which is helpful to the clinical judgment of the nature of the disease and the formulation of treatment plans.

关 键 词：超声内镜引导下细针穿刺活组织检查 肉眼现场评估 消化道及周围占位性疾病 

分 类 号：R57[医药卫生—消化系统]