Implications for brainstem recovery from studies in primates after sensory loss from arm  

作　　者：Jamie L.Reed Hui-Xin Qi Jon H.Kaas 

机构地区：[1]Department of Psychology,Vanderbilt University,Nashville,TN,USA

出　　处：《Neural Regeneration Research》2024年第3期479-480,共2页中国神经再生研究（英文版）

基　　金：supported by National Institute of Health Grant NINDS NS16446 to JHK and NS067017 to HXQ;supported by NIH NINDS NS129982 and NIH NEI EY002686 to JHK

摘　　要：For decades,researchers have known that when neurons lose their activating inputs,they can atrophy and even die.For example,removing sensory nerve inputs from the arm to the spinal cord after amputation or cutting the spinal nerves can shrink the post-synaptic target zones(e.g.,Woods et al.,2000).From touch receptors for the hand and arm,primary nerve afferents enter the spinal cord,and axons travel in the dorsal columns to target the cuneate nucleus(Cu)of the brainstem on the same side of the body(Figure 1).When sensory loss is unilateral,the overwhelming result is for the associated primary target zone to shrink in total size(cross-sectional area),as compared to the size of the opposite side.

关 键 词：BRAINSTEM shrink removing 

分 类 号：R338[医药卫生—人体生理学]