Amyotrophic lateral sclerosis(ALS) is a neurodegenerative disease that causes the progressive loss of both upper and lower motor neurons in the brain,brainstem,and spinal cord.The exact mechanisms of ALS are still unc...
supported by the Huazhong University of Science and Technology(2024JCYJ044 and 2023JCYJ033);the Key Research and Development ProgramofWuhan(2024020702030123);the Major Program(JD)of Hubei Province(2023BAA005);the National Natural Science Foundation of China(92148206 and 82071330);the Research Fund of Tongji Hospital(2022B37).
The brainstem,often referred to as the“vital center of life,”controls functions such as breathing,heartbeat,consciousness,and sensory and motor functions.It is densely packed with structures responsible for critical...
supported by the National Natural Science Foundation of China(31925019 to P.C.);the STI 2030 Major Projects(2021ZD0202701to P.C.);the New Cornerstone Science Foundation through the XPLORER PRIZE(to P.C.).All data are archived in NIBS.
Cough is a vital defensive reflex for expelling harmful substances from the airway.The sensory afferents for the cough reflex have been intensively studied.However,the brain mechanisms underlying the cough reflex rema...
supported by National Institute of Health Grant NINDS NS16446 to JHK and NS067017 to HXQ;supported by NIH NINDS NS129982 and NIH NEI EY002686 to JHK
For decades,researchers have known that when neurons lose their activating inputs,they can atrophy and even die.For example,removing sensory nerve inputs from the arm to the spinal cord after amputation or cutting the...
Hainan Clinical Medical Center Construction Project(2021);Excellent Talent Team of Hainan Province(No.QRCBT202121);Key R&D Program of Hainan Province(No.ZDYF2022SHFZ109)。
Objective:The aim was to analyse the clinical features of leptomeningeal metastasis with banded high signal in the brainstem.Methods:In this paper,we report two cases of lung adenocarcinoma with soft meningeal metasta...
supported by Guangzhou Municipal Science and Technology Bureau(No.2024A04J5124)。
INTRODUCTION The medulla oblongata is located at the lowest end of the brainstem.Damage to the ambiguous nucleus at the level of the upper medulla oblongata can lead to swallowing disorders,paralysis of the ipsilatera...
Accurate localization of cranial nerves and responsible blood vessels is important for diagnosing trigeminal neuralgia(TN)and hemifacial spasm(HFS).Manual delineation of the nerves and vessels on medical images is tim...
Objective To investigate whether vestibular-evoked myogenic potentials(VEMP)can be used to assess brainstem and its supplementary diagnostic value in patients with early-stage Parkinson’s disease(PD).Methods A total ...
This work was supported by the National Key R&D Program of China(2021YFA1101804);the National Natural Science Foundation of China(82000985 and 82101217);the Strategic Priority Research Program of Chinese Academy of Science(XDB32060100);a Shanghai Municipal Science and Technology Major Project(2018SHZDZX05).
Dear Editor,Inner ear auditory neurons,which are also referred as to spiral ganglion neurons(SGNs),bridge sound-receptor hair cells(HCs)to the cochlear nucleus in the brainstem[1].Two types of SGN exist:type I SGNs(95...
Purpose:Misophonia is not investigated much from an audiological perspective.Our study aims to examine the processing of the auditory retro-cochlear pathways in individuals with misophonia.Methods:A cross-sectional st...