Lypd1-DTR/+: A New Mouse Model for Specifically Damaging the Type Ic Spiral Ganglion Neurons of the Cochlea  

作　　者：Di Zhang Minhui Ren ZhengHong Bi Yunpeng Gu Shuting Li Guangqin Wang Xiang Li Zhiyong Liu 

机构地区：[1]Institute of Neuroscience,State Key Laboratory of Neuroscience,CAS Center for Excellence in Brain Science and Intelligence Technology,Chinese Academy of Sciences,Shanghai,200031,China [2]University of Chinese Academy of Sciences,Beijing,100049,China [3]Shanghai Center for Brain Science and Brain-Inspired Intelligence Technology,Shanghai,201210,China

出　　处：《Neuroscience Bulletin》2023年第9期1459-1462,共4页神经科学通报（英文版）

基　　金：This work was supported by the National Key R&D Program of China(2021YFA1101804);the National Natural Science Foundation of China(82000985 and 82101217);the Strategic Priority Research Program of Chinese Academy of Science(XDB32060100);a Shanghai Municipal Science and Technology Major Project(2018SHZDZX05).

摘　　要：Dear Editor,Inner ear auditory neurons,which are also referred as to spiral ganglion neurons(SGNs),bridge sound-receptor hair cells(HCs)to the cochlear nucleus in the brainstem[1].Two types of SGN exist:type I SGNs(95%),which innervate inner HCs(IHCs),and type II SGNs(only 5%),which form synapses with outer HCs(OHCs)[1,2].

关 键 词：AUDITORY BRAINSTEM COCHLEAR 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R-332[医药卫生—临床医学]