脑性瘫痪儿童的头颅MRI预期特征探讨  

Prospective Features of Brain MRI in Children with Cerebral Palsy

作　　者：马德有[1] 袁俊英[1] 王以文 孙二亮[1] 张小安[1] Ma De-you;Yuan Jun-ying;Wang yi-wen;Sun Er-liang;Zhang Xiao-an(The Third Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,Henan Province,China)

机构地区：[1]郑州大学第三附属医院,河南郑州450000

出　　处：《中国CT和MRI杂志》2023年第8期1-3,共3页Chinese Journal of CT and MRI

基　　金：国家自然科学基金(81870983)。

摘　　要：目的探讨脑性瘫痪儿童MRI的预期特征。方法以诊断为依据,回顾性纳入了符合标准的991例脑性瘫痪患儿的头颅MRI,并分为2类:正常和异常磁共振成像。然后比较两组之间的6个因素:早产、围产期高危因素、共患病、CP分型、粗大运动功能分级(GMFCS)、手功能分级(MACS)。结果大约10%的脑瘫儿童有正常的MRI,无围产期高危因素的受试者拥有正常磁共振的可能性是有高危因素史的5.518倍,痉挛性双瘫、不随意运动型和共济失调型的受试者MRI正常率是痉挛性偏瘫、痉挛性四肢瘫、混合型受试者的2.045倍,GMFCSⅠ-Ⅲ的受试者MRI正常率是GMFCSⅣ-Ⅴ的1.610倍,共患病≤1的受试者MRI正常率是共患病>1的2.131倍,与早产、手功能分级没有明显的相关性。结论围产期高危因素、共患病、CP分型、粗大运动功能分级(GMFCS)可用于脑性瘫痪儿童的头颅MRI预测,早产和手功能分级(MACS)在此方面意义不大。Objective To investigate the expected features of MRI in children with cerebral palsy.Methods Based on the diagnosis,retrospective inclusion of 991 head MRI images of children with cerebral palsy who met the criteria and were classified into 2 categories:normal and abnormal magnetic resonance imaging.Six factors were compared between the two groups:preterm birth,perinatal risk factors,comorbidities,CP classification,gross motor function classification(GMFCS),and hand function classification(MACS).Results With normal MRI about 10%of children with cerebral palsy.Subjects without perinatal high-risk factors are 5.518 times more likely to have normal MRI than those with history of high-risk factors.Subjects with spastic diplegia,involuntary motility and ataxia have 2.045 times more normal MRI than those with spastic hemiplegia,spastic quadriplegia and mixed type.The normal MRI rate of subjects with GMFCSⅠ-Ⅲwas 1.610 times higher than that of subjects with GMFCSⅣ-Ⅴ,and the normal MRI rate of subjects with comorbidities≤1 was 2.131 times higher than that of subjects with comorbidities>1.There was no obvious correlation with preterm birth and hand function classification.Conclusion Perinatal risk factors,comorbidities,CP classification and gross motor function classification(GMFCS)can be used to predict brain MRI in children with cerebral palsy,while preterm birth and hand function classification(MACS)have little significance in this respect.

关 键 词：脑性瘫痪 头颅MRI GMFCS分级 MACS分级 

分 类 号：R742.3[医药卫生—神经病学与精神病学]