近视性屈光参差少年儿童眼部屈光生物学参数的临床研究  

Clinical study on the biological parameters of eye refraction in children with myopic anisometropia

作　　者：宋红欣[1] 孙璐 王庆强[3] Song Hongxin;Sun Lu;Wang Qingqiang(Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University,Beijing Key Laboratory of Ophthalmology and Visual Science,Beijing 100730,China;Aier Intech Eye Hospital,Beijing 100021,China;Department of Opthamology,Shengli Oilfield Central Hospital of Shandong Dongying,Dongying 257034,China)

机构地区：[1]首都医科大学附属北京同仁医院眼科中心、北京市眼科研究所眼科学与视觉科学北京市重点实验室,100730 [2]爱尔英智眼科医院,北京100021 [3]山东东营胜利油田中心医院眼科,257034

出　　处：《中华眼科医学杂志（电子版）》2023年第2期88-93,共6页Chinese Journal of Ophthalmologic Medicine(Electronic Edition)

基　　金：首都卫生发展科研专项项目(2022-1G-4083)。

摘　　要：目的探讨单眼近视性屈光参差对少年儿童眼部屈光参数的影响,分析眼轴变化与屈光度变化相关性。方法收集2017年7月至2020年5月于首都医科大学附属北京同仁医院眼科中心就诊的单眼近视性屈光参差少年儿童患者70例(140只眼)。其中,男性28例(56只眼),女性42例(84只眼),年龄8~15岁,平均(11.0±1.9)岁。全部患者均测量眼轴长度、角膜曲率平坦K值、角膜曲率陡峭K值、角膜平坦E值及角膜陡峭E值;散瞳验光并计算等效球镜屈光度。患者的年龄、眼轴长度、等效球镜屈光度、眼轴长度差值、屈光度差值、角膜曲率平坦K值、角膜曲率陡峭K值、角膜平坦E值及角膜陡峭E值均符合正态性分布,采用(±s)进行描述。健眼和患眼各生物学参数的比较采用配对t检验;按年龄段分为8~10岁组和11~15岁组,采用Pearson相关系数和线性回归分析双眼眼轴长度差值和屈光度差值的相关性。结果70例(140只眼)患者中,男性28例(56只眼),占40%;女性42例(84只眼),占60%。右眼近视患者51例(51只眼),占72.86%;左眼近视患者19例(19只眼),占27.14%。患眼的眼轴长度为(24.49±0.84)mm,健眼的眼轴长度为(23.54±0.73)mm,两组之间差异具有统计学意义(t=15.626,P<0.05);患眼等效球镜度为(-2.39±1.05)D,健眼等效球镜度为(-0.07±0.32)D,双眼差异具有统计学意义(t=-18.214,P<0.05);患眼角膜曲率平坦K值为(42.74±1.28),健眼角膜曲率平坦K值为(42.75±1.29),双眼差异无统计学意义(t=0.344,P>0.05);患眼角膜曲率陡峭K值为(44.03±1.44),健眼角膜曲率陡峭K值为(43.92±1.38),双眼差异具有统计学意义(t=-3.392,P<0.05);患眼角膜平坦E值为(0.64±0.09),健眼角膜平坦E值为(0.66±0.11),双眼差异具有统计学意义(t=2.672,P<0.05),患眼角膜陡峭E值为(0.50±0.20),健眼角膜陡峭E值为(0.53±0.20),双眼差异无统计学意义(t=1.226,P>0.05)。总体、8~10岁组及11~15岁组患者双眼眼轴长度的差值分别为(0.Objective The aim of this study was to assess the impact of monocular myopic anisometropia on the refractive parameters of children′s eyes and analyze the correlation between axial changes and refractive changes.MethodsFrom July 2017 to May 2020,70 cases(140 eyes)of children with monocular myopic anisometropia were collected from the Eye Center of Beijing Tongren Hospital affiliated to Capital Medical University.Among them,there were 28 males(56 eyes)and 42 females(84 eyes),aged 8 to 15 years with an average age of(11.0±1.9)years.All patients were measured for axial length,corneal curvature flatness K value,corneal curvature steepness K value,corneal flatness E value,and corneal steepness E value.Astigmatic refraction and calculation of equivalent spherical diopter were performed.The patients′age,axial length,equivalent spherical refractive index,D-value of axial length,D-value of refractive index,corneal curvature flatness K value,steep K value,corneal flatness E value,and steep E value conformed to a normal distribution,and were described by±s.The biological parameters between healthy and affected eyes was compared using paired t testing.According to age range,they were divided into 8 to 10 years old group and 11 to 15 years old group.The correlation between D-value of binocular axial length and D-value of refractive index were performed Pearson correlation coefficient and linear regression analysis.ResultsAmong 70 patients(140 eyes),there were 28 males(56 eyes),accounting for 40%,and 42 females(84 eyes),accounting for 60%.There were 51 patients(51 eyes)with right myopia,accounting for 72.86%,and 19 patients(19 eyes)with left myopia,accounting for 27.14%.The axial length of the affected eye was(24.49±0.84)mm,while the axial length of the healthy eye was(23.54±0.73)mm.There were statistically significant differences between the two groups(t=15.626,P<0.05).The equivalent spherical diopter of the affected eye and the healthy eye was(-2.39±1.05)D and(-0.07±0.32)D,respectively.The difference between the tw

关 键 词：近视 屈光参差 屈光参数 眼轴长度 

分 类 号：R778.11[医药卫生—眼科]