低浓度阿托品在儿童近视眼防控中应用的研究进展  

Advance on the application of the low concentration atropine for the prevention and control of myopia in children

作　　者：赵艳 朱丹[2] Zhao Yan;Zhu Dan(The First Clinical Medical School,Inner Mongolia Medical University,Hohhot 010020,China;Department of Ophthalmology,the Affiliated Hospital of Inner Mongolia Medical University,Hohhot 010020,China)

机构地区：[1]内蒙古医科大学第一临床医学院,呼和浩特010020 [2]内蒙古医科大学附属医院眼科,呼和浩特010020

出　　处：《中华眼科医学杂志（电子版）》2023年第2期124-128,共5页Chinese Journal of Ophthalmologic Medicine(Electronic Edition)

基　　金：国家自然科学基金项目(81860178)。

摘　　要：近视眼是一个全球性问题,在世界范围内正以流行病的速度增长。除了常规治疗带来的负担外,高度近视眼更会导致威胁视力的并发症。在儿童时控制近视眼的发生和发展可以降低与高度近视眼相关的发病风险。近视眼的发展可以通过各种光学、环境及药物策略来减缓。其中,阿托品被证明具有有效性。本文中笔者整理回顾近年来国内外相关研究,对低浓度阿托品在儿童近视眼防控中的作用机制、使用时机选择、有效性、安全性、不良反应、停药反应及联合治疗方案进行综述,为其临床广泛应用提供依据。Myopia is a global problem that is growing at an epidemic rate in the worldwide.In addition to the burden of conventional treatment,high myopia is more likely to lead to vision-threatening complications.Controlling the onset and development of myopia in children can reduce the risk of developing the disease associated with high myopia.The development of myopia can be slowed by a variety of optical,environmental,and pharmaceutical strategies,of which atropine has been shown to be effective.The documents at home and abroad in recent years about the mechanism of action,timing of use,effectiveness,safety,adverse reactions,withdrawal reactions,and combined treatment plans of low concentration atropine in the control of myopia in children were reviewed in this paper,which could provide a basis for its widely clinical application.

关 键 词：低浓度阿托品 近视眼 有效性 安全性 

分 类 号：R778.11[医药卫生—眼科]