基于2种模型的原发性肝癌患者肝动脉栓塞化疗术后延迟性恶心呕吐影响因素分析  

Analysis of influencing factors of delayed nausea and vomiting in patients with primary liver cancer after transarterial chemoembolization based on two models

作　　者：史金凤 王娜 司文 杨青 李沛 赵蓉 郭晶 Shi Jinfeng;Wang Na;Si Wen;Yang Qing;Li Pei;Zhao Rong;Guo Jing(Department of Oncology,the Second Affiliated Hospital of Air Force Military Medical University,Xi′an 710038,China;Liver Diseases Center,Department of Infectious Diseases,the Second Affiliated Hospital of Air Force Military Medical University,Xi′an 710038,China)

机构地区：[1]中国人民解放军空军军医大学第二附属医院肿瘤科,西安710038 [2]中国人民解放军空军军医大学第二附属医院传染科肝病中心,西安710038

出　　处：《中国实用护理杂志》2023年第21期1628-1635,共8页Chinese Journal of Practical Nursing

摘　　要：目的采用Logistic回归与决策树模型分析原发性肝癌患者肝动脉栓塞化疗术后延迟性恶心呕吐的影响因素。方法本研究为横断面研究,采用便利取样法选取2021年3月至2022年6月在中国人民解放军空军军医大学第二附属医院行肝动脉栓塞化疗的原发性肝癌患者236例为研究对象,收集患者延迟性恶心呕吐相关因素,分别建立Logistic回归与决策树模型,并比较2种模型的差异。结果原发性肝癌患者肝动脉栓塞化疗术后延迟性恶心呕吐的发生率为45.34%(107/236)。Logistic回归模型显示,年龄、是否焦虑、是否有睡眠障碍、化疗药物致吐风险等级、栓塞剂类型、术后24 h疼痛情况是原发性肝癌患者肝动脉栓塞化疗术后延迟性恶心呕吐的影响因素(均P<0.05)。决策树模型显示,年龄、是否有睡眠障碍、化疗药物致吐风险等级、栓塞剂类型、术后24 h疼痛情况是原发性肝癌患者肝动脉栓塞化疗术后延迟性恶心呕吐的影响因素(均P<0.05)。Logistic回归模型、决策树模型、2种模型联合诊断分类正确率分别为72.9%、71.2%、72.0%,ROC曲线下面积分别为0.778、0.781、0.806,三者比较差异均无统计学意义(均P>0.05)。结论Logistic回归与决策树模型对原发性肝癌患者肝动脉栓塞化疗术后延迟性恶心呕吐影响因素的分析结果一致性较高,可联合应用2种模型,为医护人员的评估和干预提供更全面的参考。ObjectiveTo analyze the influencing factors of delayed nausea and vomiting in patients with primary liver cancer after transarterial chemoembolization based on Logistic regression model and decision tree model.MethodsThis was a cross-sectional study.A total of 236 patients with primary liver cancer after transarterial chemoembolization in The Second Affiliated Hospital of Air Force Military Medical University from March 2021 to June 2022 were conveniently selected as the research subjects.The factors related to delayed nausea and vomiting were collected,and Logistic regression and decision tree models were established,respectively,and the differences between the two models were compared.ResultsThe incidence of delayed nausea and vomiting of patients with primary liver cancer after transarterial chemoembolization was 45.34%(107/236).Logistic regression model showed that age,anxiety,sleep disorder,emetic risk level of chemotherapeutic drugs,embolic agent type,and pain 24 hours after surgery were the influencing factors of delayed nausea and vomiting in patients with primary liver cancer after transarterial chemoembolization(all P<0.05).Decision tree model showed that age,sleep disorder,emetic risk level of chemotherapeutic drugs,embolic agent type,and pain 24 hours after surgery were the influencing factors of delayed nausea and vomiting in patients with primary liver cancer after transarterial chemoembolization(all P<0.05).The classification accuracy rates of Logistic regression,decision tree model and combined diagnosis of two models were 72.9%,71.2%and 72.0%respectively;the areas under the ROC curve were 0.778,0.781 and 0.806 respectively,with no significant difference(all P>0.05).ConclusionsThe analysis results of Logistic regression and decision tree model on the influencing factors of delayed nausea and vomiting in patients with primary liver cancer after transarterial chemoembolization are highly consistent,which can be combined to provide a more comprehensive reference for the evaluation and intervention of

关 键 词：肝肿瘤 LOGISTIC模型 决策树 手术后恶心呕吐 肝动脉栓塞化疗 影响因素 

分 类 号：R735.7[医药卫生—肿瘤]